Kang J Y, Dhar A, Pollok R, Leicester R J, Benson M J, Kumar D, Melville D, Neild P J, Tibbs C J, Maxwell J D
Department of Gastroenterology, St George's Hospital, London, UK.
Aliment Pharmacol Ther. 2004 Apr 1;19(7):765-9. doi: 10.1111/j.1365-2036.2004.01908.x.
Colonic diverticular disease is more common in Western populations than in developing countries.
To determine whether the frequency of colonic diverticular disease is different in British patients of Indian-subcontinent Asian origin compared with other ethnic groups.
All colonoscopies performed over a 3-year period in a London hospital were studied. Patients of Indian-subcontinent Asian origin were identified by name.
Five of 134 Indian-subcontinent Asian males (4%) had colonic diverticular disease, compared with 278 of 1268 patients of other ethnic groups (22%; P < 0.001). Five of 91 Indian-subcontinent Asian females (6%) had colonic diverticular disease, compared with 333 of 1486 patients of other ethnic groups (23%; P < 0.001). Although patients of Indian-subcontinent Asian origin (54.8 +/- 15.8 years) were younger than those of other ethnic groups (60.3 +/- 17.8 years; P < 0.0001), the ethnic difference in the frequency of diverticular disease persisted even when age was taken into account.
There is a lower frequency of colonic diverticular disease in Indian-subcontinent Asians presenting for colonoscopy, compared with other ethnic groups. This cannot be explained by sex or age differences. Our findings require confirmation, but may provide opportunities for research into the aetiology of colonic diverticular disease.
结肠憩室病在西方人群中比在发展中国家更常见。
确定印度次大陆亚洲裔英国患者中结肠憩室病的发生率与其他种族群体相比是否存在差异。
对伦敦一家医院3年内进行的所有结肠镜检查进行研究。通过姓名识别印度次大陆亚洲裔患者。
134名印度次大陆亚洲裔男性中有5人（4%）患有结肠憩室病，而其他种族群体的1268名患者中有278人（22%；P<0.001）。91名印度次大陆亚洲裔女性中有5人（6%）患有结肠憩室病，而其他种族群体的1486名患者中有333人（23%；P<0.001）。尽管印度次大陆亚洲裔患者（54.8±15.8岁）比其他种族群体的患者（60.3±17.8岁；P<0.0001）年轻，但即使考虑年龄因素，憩室病发生率的种族差异仍然存在。
接受结肠镜检查的印度次大陆亚洲人中结肠憩室病的发生率低于其他种族群体。这不能用性别或年龄差异来解释。我们的研究结果需要证实，但可能为结肠憩室病病因学的研究提供机会。
