Ham Melissa R, Okada Pamela, White Perrin C
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9063, USA.
Pediatr Diabetes. 2004 Mar;5(1):39-43. doi: 10.1111/j.1399-543X.2004.00032.x.
Diabetic ketoacidosis (DKA) is a serious complication of diabetes mellitus marked by characteristic biochemical derangements. Diagnosis and management involve frequent evaluation of these biochemical parameters. Reliable bedside equivalents for these laboratory studies may help reduce the time to treatment and reduce costs.
We evaluated the precision and bias of a bedside serum ketone meter in the acute care setting. Serum ketone results using the Precision Xtra glucometer/ketone meter (Abbott Laboratories, MediSense Products Inc., Bedford, MA, USA) correlated strongly with the Children's Medical Center of Dallas' laboratory values within the meter's value range.
Meter ketone values steadily decreased during the treatment of DKA as pH and CO(2) levels increased and acidosis resolved.
Therefore, the meter may be useful in monitoring therapy for DKA. This meter may also prove useful in identifying patients at risk for DKA in physicians' offices or at home.
糖尿病酮症酸中毒（DKA）是糖尿病的一种严重并发症，其特征为具有特定的生化紊乱。诊断和治疗需要频繁评估这些生化参数。这些实验室检查可靠的床旁等效方法可能有助于缩短治疗时间并降低成本。
我们在急性护理环境中评估了一种床旁血清酮仪的精密度和偏差。使用Precision Xtra血糖仪/酮仪（美国马萨诸塞州贝德福德市雅培实验室美迪信产品公司）测得的血清酮结果在该仪器的数值范围内与达拉斯儿童医疗中心的实验室值高度相关。
在DKA治疗期间，随着pH值和二氧化碳水平升高以及酸中毒得到缓解，仪器测得的酮值稳步下降。
因此，该仪器可能有助于监测DKA的治疗。该仪器在医生办公室或家中识别有DKA风险的患者方面可能也很有用。
