Ward Jonathan J, McGuffin Liam J, Bryson Kevin, Buxton Bernard F, Jones David T
Bioinformatics Group, Department of Computer Science, University College London, Gower Street, London, WC1E 6BT, UK.
Bioinformatics. 2004 Sep 1;20(13):2138-9. doi: 10.1093/bioinformatics/bth195. Epub 2004 Mar 25.
Dynamically disordered regions appear to be relatively abundant in eukaryotic proteomes. The DISOPRED server allows users to submit a protein sequence, and returns a probability estimate of each residue in the sequence being disordered. The results are sent in both plain text and graphical formats, and the server can also supply predictions of secondary structure to provide further structural information.
The server can be accessed by non-commercial users at http://bioinf.cs.ucl.ac.uk/disopred/
动态无序区域在真核生物蛋白质组中似乎相对丰富。DISOPRED服务器允许用户提交蛋白质序列,并返回序列中每个残基无序的概率估计值。结果以纯文本和图形格式发送,该服务器还可以提供二级结构预测以提供更多结构信息。