Malone Margaret, Alger-Mayer Sharon
Department of Pharmacy Practice, Albany College of Pharmacy, Albany Medical College, Albany, New York 12208, USA.
Obes Res. 2004 Mar;12(3):473-81. doi: 10.1038/oby.2004.53.
This study evaluated gastric bypass surgery outcomes according to presurgical binge eating severity.
Adult patients completed assessment questionnaires including the Short Form-36, Gormally Binge Eating Scale (BES), and Beck Depression Inventory (BDI) before and 12 months after surgery.
One hundred nine patients (18 men, 91 women) were recruited. Based on their baseline BES scores, patients were non- [n = 52 (48%)], moderate [n = 31 (28%)], or severe [n = 26 (24%)] binge eaters. Although the percentage of excess weight loss was greatest after 12 months in the severe binge eaters, the difference among groups was not significant. Severe binge eaters had higher baseline BDI scores than either non- or moderate binge eaters (p = 0.001). After surgery, BDI scores declined significantly in all groups from the baseline scores but remained higher postoperatively in the severe binge eaters (p = 0.018). BES scores declined significantly (p = 0.000) after surgery within all groups. There was no difference in the Short Form-36 physical component summary scores at baseline among groups. Mental component summary scores were significantly lower in the severe binge eaters (p = 0.001). After surgery, there was no difference among groups in either physical or mental component summary scores.
In conclusion, data from the present study suggest that patients have similar outcomes in terms of improved depression scores, binge eating behavior, and health-related quality of life regardless of their binge eating severity before surgery. Patients with the most severe binge eating behavior before surgery showed the most improvement when assessed 12 months after surgery.
本研究根据术前暴饮暴食严重程度评估胃旁路手术的结果。
成年患者在手术前和手术后12个月完成评估问卷，包括简短健康调查问卷（Short Form-36）、戈尔马利暴饮暴食量表（Gormally Binge Eating Scale，BES）和贝克抑郁量表（Beck Depression Inventory，BDI）。
招募了109名患者（18名男性，91名女性）。根据他们的基线BES评分，患者分为非暴饮暴食者[n = 52（48%）]、中度暴饮暴食者[n = 31（28%）]或重度暴饮暴食者[n = 26（24%）]。尽管重度暴饮暴食者在12个月后超重减轻的百分比最大，但各组之间的差异并不显著。重度暴饮暴食者的基线BDI评分高于非暴饮暴食者和中度暴饮暴食者（p = 0.001）。手术后，所有组的BDI评分均较基线评分显著下降，但重度暴饮暴食者术后仍较高（p = 0.018）。所有组术后BES评分均显著下降（p = 0.000）。各组基线时简短健康调查问卷的身体成分总结评分无差异。重度暴饮暴食者的心理成分总结评分显著较低（p = 0.001）。手术后，各组在身体或心理成分总结评分方面均无差异。
总之，本研究数据表明，无论术前暴饮暴食严重程度如何，患者在抑郁评分改善、暴饮暴食行为和健康相关生活质量方面的结果相似。术前暴饮暴食行为最严重的患者在术后12个月评估时改善最大。
