Morseth M S, Hanvold S E, Rø Ø, Risstad H, Mala T, Benth J Šaltytė, Engström M, Olbers T, Henjum S
Oslo and Akershus University College of Applied Science, Postbox 4 St. Olavs plass, 0130, Oslo, Norway.
Department of Morbid Obesity and Bariatric Surgery, Oslo University Hospital, Postboks 4959, Nydalen, 0424, Oslo, Norway.
Obes Surg. 2016 Mar;26(3):588-94. doi: 10.1007/s11695-015-1790-8.
This study assessed eating disorder pathology in persons with obesity before and after Roux-en-Y gastric bypass (RYGB) and biliopancreatic diversion with duodenal switch (DS), in a 5-year follow-up study.
Sixty participants with BMI 50-60 kg/m(2) were randomly assigned to RYGB (n = 31) or DS (n = 29). The participants completed the Eating Disorder Examination-Questionnaire (EDE-Q) before and 6 months, 1 year, 2 years, and 5 years after surgery.
Before surgery, the prevalence of objective bulimic episodes was 29 % in the RYGB group and 32 % in the DS group. The prevalence improved during the first 12 months after surgery in both groups. After 5 years, the prevalence of objective bulimic episodes was 22 % in the RYGB group and 7 % in the DS group. The difference between groups throughout follow-up was non-significant (logistic regression model). A linear mixed model showed that global EDE-Q score was not a significant predictor for weight loss after surgery, but participants reporting objective bulimic episodes before surgery had significantly lower BMI than those with no episodes after 2 years (p = 0.042) and 5 years (p = 0.013). Global EDE-Q score was significantly lower in the DS group after 5 years (p = 0.009) (linear mixed model).
Objective bulimic episodes but not global EDE-Q score before surgery predicted greater weight loss after RYGB and DS. The DS group had a significantly lower global EDE-Q score than the RYGB group 5 years after surgery.
在一项为期5年的随访研究中,本研究评估了肥胖症患者在接受Roux-en-Y胃旁路术(RYGB)和胆胰转流十二指肠转位术(DS)前后的饮食失调病理情况。
60名体重指数(BMI)为50 - 60kg/m²的参与者被随机分配至RYGB组(n = 31)或DS组(n = 29)。参与者在手术前以及术后6个月、1年、2年和5年完成饮食失调检查问卷(EDE-Q)。
手术前,RYGB组客观暴食发作的患病率为29%,DS组为32%。两组在术后的前12个月患病率均有所改善。5年后,RYGB组客观暴食发作的患病率为22%,DS组为7%。在整个随访过程中,两组之间的差异无统计学意义(逻辑回归模型)。线性混合模型显示,EDE-Q总分并非术后体重减轻的显著预测指标,但术前报告有客观暴食发作的参与者在术后2年(p = 0.042)和5年(p = 0.013)时的BMI显著低于无发作的参与者。5年后,DS组的EDE-Q总分显著更低(p = 0.009)(线性混合模型)。
术前的客观暴食发作而非EDE-Q总分可预测RYGB和DS术后更大程度的体重减轻。术后5年,DS组的EDE-Q总分显著低于RYGB组。