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胃旁路手术后的生活质量:一项横断面研究。

Quality of life after gastric bypass surgery: a cross-sectional study.

作者信息

Dymek Maureen P, Le Grange Daniel, Neven Kim, Alverdy John

机构信息

Department of Psychiatry and. Department of Surgery, The University of Chicago Hospitals, Chicago, Illinois, USA.

出版信息

Obes Res. 2002 Nov;10(11):1135-42. doi: 10.1038/oby.2002.154.

Abstract

OBJECTIVE

Numerous reports document significant weight loss after gastric bypass; however, there is little objective data on postsurgical changes in health-related quality of life (HRQL).

RESEARCH METHODS AND PROCEDURES

This study examined HRQL in four groups of patients: presurgery (T1), several weeks postsurgery (T2), 6 months postsurgery (T3), and 1 year postsurgery (T4). Subjects were given three HRQL measures: the short form 36 (SF-36), the Impact of Weight on Quality of Life-Lite Questionnaire (IWQOL-Lite), and the Bariatric Analysis and Reporting Outcome System (BAROS). Subjects also completed the Beck Depression Inventory (BDI) and the Rosenberg Self-Esteem Scale (RSE).

RESULTS

There were no significant differences among the groups on demographics or presurgical body mass index. Results showed significant differences between T1 and T2 on several SF-36 and IWQOL-Lite subscales, as well as the RSE and BDI. Significant differences were found on all measures between T2 and T3. Significant differences were found on all subscales of the IWQOL-Lite, but no subscales of the SF-36, the RSE, or the BDI between T3 and T4.

DISCUSSION

This study is the first to objectively document these differences in several objective measures of HRQL, depression, and self-esteem after gastric bypass in a large sample. It is notable that many differences are apparent within several weeks after surgery. Furthermore, results indicate that the IWQOL-Lite may be more sensitive than the SF-36 to the changes of quality of life that gastric bypass patients report.

摘要

目的

众多报告记录了胃旁路术后显著的体重减轻情况;然而,关于术后健康相关生活质量(HRQL)变化的客观数据却很少。

研究方法与步骤

本研究对四组患者的HRQL进行了检查:术前(T1)、术后几周(T2)、术后6个月(T3)和术后1年(T4)。受试者接受了三项HRQL测量:简短健康调查问卷36项版本(SF - 36)、体重对生活质量影响简易问卷(IWQOL - Lite)以及肥胖症分析与报告结果系统(BAROS)。受试者还完成了贝克抑郁量表(BDI)和罗森伯格自尊量表(RSE)。

结果

各组在人口统计学特征或术前体重指数方面无显著差异。结果显示,在几个SF - 36和IWQOL - Lite子量表以及RSE和BDI上,T1和T2之间存在显著差异。在T2和T3之间的所有测量指标上均发现显著差异。在IWQOL - Lite的所有子量表上发现显著差异,但在T3和T4之间,SF - 36、RSE或BDI的任何子量表上均未发现显著差异。

讨论

本研究首次在大样本中客观记录了胃旁路术后在HRQL、抑郁和自尊的几个客观测量指标上的这些差异。值得注意的是,许多差异在术后几周内就很明显。此外,结果表明,IWQOL - Lite可能比SF - 36对胃旁路手术患者报告的生活质量变化更敏感。

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