Ekelund Ulf, Franks Paul W, Wareham Nicolas J, Aman Jan
Medical Research Council Epidemiology Unit, Cambridge, United Kingdom.
Obes Res. 2004 Mar;12(3):513-20. doi: 10.1038/oby.2004.58.
To test whether resting oxygen uptake (VO(2)), submaximal VO(2), and maximal VO(2) (VO(2max)) differs between obese adolescents (n = 18; BMI > 30) and a matched normal-weight control group after adjustment for differences in fat-free mass (FFM) and fat mass (FM).
FFM and FM were assessed by DXA. Resting VO(2), submaximal VO(2), and VO(2max) were measured by indirect calorimetry.
There was no difference in resting VO(2) between groups after adjusting for FFM and FM. Submaximal VO(2) did not differ between groups after adjusting for body weight. Percentage VO(2max) and NET VO(2) (VO(2max) - resting VO(2)) were significantly higher in the obese group during submaximal exercise, however not after adjusting for body weight. VO(2max) was not significantly different between groups after adjusting for FFM.
When body compositions are appropriately controlled for, resting VO(2), submaximal VO(2), and VO(2max) do not differ between obese and normal-weight adolescents. These data suggested that the higher relative VO(2) observed in obese adolescent subjects is due to their higher FM and not to an impaired VO(2max) even though they may be less physically active.
在对无脂肪量（FFM）和脂肪量（FM）差异进行校正后，测试肥胖青少年（n = 18；BMI > 30）与匹配的正常体重对照组之间静息摄氧量（VO₂）、次最大摄氧量和最大摄氧量（VO₂max）是否存在差异。
通过双能X线吸收法评估FFM和FM。通过间接测热法测量静息VO₂、次最大VO₂和VO₂max。
在对FFM和FM进行校正后，两组之间静息VO₂无差异。在对体重进行校正后，两组之间次最大VO₂无差异。然而，在次最大运动期间，肥胖组的VO₂max百分比和净VO₂（VO₂max - 静息VO₂）显著更高，但在对体重进行校正后则不然。在对FFM进行校正后，两组之间VO₂max无显著差异。
当对身体成分进行适当控制时，肥胖青少年与正常体重青少年之间的静息VO₂、次最大VO₂和VO₂max无差异。这些数据表明，肥胖青少年受试者中观察到的较高相对VO₂是由于其较高的FM，而不是VO₂max受损，尽管他们可能身体活动较少。
