Identification of decomposition products of 1,1'-ethylidenebis [L-tryptophan], a compound associated with eosinophilia-myalgia syndrome.

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作者信息

Driskell W J, Ashley D L, Grainger J, Sirimanne S R, Mazzola E P, Page S W, Needham L L, Hill R H

机构信息

Center for Environmental Health and Injury Control, Centers for Disease Control, Atlanta, Georgia 30333.

出版信息

Bull Environ Contam Toxicol. 1992 May;48(5):679-87. doi: 10.1007/BF00195987.

DOI:10.1007/BF00195987

PMID:1504513

Abstract

摘要

相似文献

Identification of decomposition products of 1,1'-ethylidenebis [L-tryptophan], a compound associated with eosinophilia-myalgia syndrome.

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1,1'-Ethylidenebis[L-tryptophan], an impurity in L-tryptophan associated with eosinophilia-myalgia syndrome, stimulates type I collagen gene expression in human fibroblasts in vitro.1,1'-亚乙基双[L-色氨酸]是L-色氨酸中与嗜酸性粒细胞增多性肌痛综合征相关的一种杂质，它在体外可刺激人成纤维细胞中I型胶原蛋白基因的表达。

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A murine model of the eosinophilia-myalgia syndrome induced by 1,1'-ethylidenebis (L-tryptophan).由1,1'-亚乙基双（L-色氨酸）诱导的嗜酸性粒细胞增多性肌痛综合征的小鼠模型。

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1,1'-Ethylidenebis[tryptophan] induces pathologic alterations in muscle similar to those observed in the eosinophilia-myalgia syndrome.1,1'-亚乙基双[色氨酸]诱导肌肉出现与嗜酸性粒细胞增多性肌痛综合征中观察到的类似病理改变。

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On-line HPLC-tandem mass spectrometry analysis of contaminants of L-tryptophan associated with the onset of the eosinophilia-myalgia syndrome.与嗜酸性粒细胞增多性肌痛综合征发病相关的L-色氨酸污染物的在线高效液相色谱-串联质谱分析

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Peak AAA fatty acid homolog contaminants present in the dietary supplement l-Tryptophan associated with the onset of eosinophilia-myalgia syndrome.膳食补充剂 l-色氨酸中存在的峰 AAA 脂肪酸同系物污染物与嗜酸性粒细胞增多性肌痛综合征的发生有关。

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Structural characterization of case-associated contaminants peak C and FF in L-tryptophan implicated in eosinophilia-myalgia syndrome.与嗜酸性粒细胞增多性肌痛综合征相关的L-色氨酸中病例相关污染物峰C和FF的结构表征

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Structure determination of disease associated peak AAA from l-Tryptophan implicated in the eosinophilia-myalgia syndrome.与嗜酸性粒细胞增多性肌痛综合征相关的、由L-色氨酸产生的疾病关联峰AAA的结构测定。

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J Mol Med (Berl). 1996 Sep;74(9):497-504. doi: 10.1007/BF00204975.

J Clin Invest. 1994 Apr;93(4):1473-80. doi: 10.1172/JCI117125.

本文引用的文献

The cause of the eosinophilia-myalgia syndrome associated with tryptophan use.

N Engl J Med. 1990 Oct 4;323(14):992-3. doi: 10.1056/NEJM199010043231412.

Eosinophilia-myalgia syndrome. Results of national surveillance.嗜酸性粒细胞增多性肌痛综合征。全国监测结果。

JAMA. 1990 Oct 3;264(13):1698-703.

An investigation of the cause of the eosinophilia-myalgia syndrome associated with tryptophan use.一项关于与使用色氨酸相关的嗜酸性粒细胞增多性肌痛综合征病因的调查。

N Engl J Med. 1990 Aug 9;323(6):357-65. doi: 10.1056/NEJM199008093230601.

Eosinophilia-myalgia syndrome associated with exposure to tryptophan from a single manufacturer.与接触单一制造商生产的色氨酸相关的嗜酸性粒细胞增多性肌痛综合征。

JAMA. 1990 Jul 11;264(2):213-7.

Characterization of "peak E," a novel amino acid associated with eosinophilia-myalgia syndrome.与嗜酸性粒细胞增多性肌痛综合征相关的新型氨基酸“E峰”的特征分析

Science. 1990 Dec 21;250(4988):1707-8. doi: 10.1126/science.2270484.

Analysis of L-tryptophan for the etiology of eosinophilia-myalgia syndrome.

MMWR Morb Mortal Wkly Rep. 1990 Aug 31;39(34):589-91.

Update: analysis of L-tryptophan for the etiology of eosinophilia-myalgia syndrome.最新消息：对嗜酸性粒细胞增多性肌痛综合征病因的L-色氨酸分析。

MMWR Morb Mortal Wkly Rep. 1990 Nov 2;39(43):789-90.

Studies on models for tetrahydrofolic acid. 7. Reactions and mechanisms of tetrahydroquinoxaline derivatives at the formaldehyde level of oxidation.四氢叶酸模型的研究。7. 四氢喹喔啉衍生物在甲醛氧化水平上的反应及机理。

J Am Chem Soc. 1976 Jun 9;98(12):3678-89. doi: 10.1021/ja00428a049.

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