Carvalho T L, Carraro A A, Lopes R A, Ribeiro R D
Faculty of Odontology, Ribeirão Preto, Brasil.
Exp Toxicol Pathol. 1992 Jun;44(3):147-9.
A previous study showed that the vas deferens of mice in the acute phase of Chagas' disease had a slight increase in the muscle layer area associated with a small decrease in the luminal area. The vas deferens of chronic chagasic mice, investigated in the present experiment, presented a marked increase in the luminal area in addition to a significant thinning of the muscle and epithelium layers. The structural alterations of the vas deferens observed in the acute and chronic phases of Chagas' disease were compared with the evolution of chagasic esophagopathy.
先前的一项研究表明，恰加斯病急性期小鼠的输精管肌层面积略有增加，管腔面积略有减小。在本实验中研究的慢性恰加斯病小鼠的输精管，除了肌肉层和上皮层显著变薄外，管腔面积还显著增加。将恰加斯病急性期和慢性期观察到的输精管结构改变与恰加斯病食管病的进展进行了比较。
