Tavares M C, Carraro A A, Favaretto A L, Petenusci S O, Lopes R A, Ribeiro R D, Carvalho T L
Faculdade de Odontologia de Ribeirão Preto, Brasil.
Exp Toxicol Pathol. 1994 Aug;46(3):243-6.
Male Wistar rats were injected i.p. with 2 x 10(5) trypomastigotes of the Bolivia strain. Fifteen days later, few parasite nests were observed in the fibromuscular layer surrounding the seminal vesicle acini of chagasic animals and no parasites were detected in the testis and ventral prostate. A significant decrease was observed in the absolute weight and fructose content of the seminal vesicle and ventral prostate of chagasic rats, which also presented a sharp decrease in plasma testosterone levels.
将2×10⁵个玻利维亚株锥鞭毛体经腹腔注射到雄性Wistar大鼠体内。15天后，在患恰加斯病动物精囊腺泡周围的纤维肌层中观察到少量寄生虫巢，而在睾丸和腹侧前列腺中未检测到寄生虫。患恰加斯病大鼠的精囊和腹侧前列腺的绝对重量和果糖含量显著降低，其血浆睾酮水平也急剧下降。
