遗传性视网膜变性的分子遗传学

Molecular genetics of inherited retinal degenerations.

作者信息

Lindsay S, Inglehearn C F, Curtis A, Bhattacharya S

机构信息

Molecular Genetics Unit Division of Human Genetics, University of Newcastle upon Tyne, UK.

出版信息

Curr Opin Genet Dev. 1992 Jun;2(3):459-66. doi: 10.1016/s0959-437x(05)80158-3.

DOI:10.1016/s0959-437x(05)80158-3

PMID:1504622

Abstract

There has recently been substantial progress in categorizing the vast range of human retinal degeneration phenotypes. A molecular approach has assigned chromosomal locations for approximately a dozen such diseases and has identified four of the genes involved.

摘要

最近，在对大量人类视网膜变性表型进行分类方面取得了重大进展。一种分子方法已确定了大约十二种此类疾病的染色体位置，并鉴定出其中四种相关基因。