Mohanty S S, Kay P R
Wrightington Hospital for Joint Diseases, Wigan, England, UK.
J Bone Joint Surg Br. 2004 Mar;86(2):266-8. doi: 10.1302/0301-620x.86b2.14129.
A retrospective review of MRSA screening showed that of a total of 8911 patients screened pre-operatively between May 1996 and February 2001, 83 (0.9%) had MRSA isolated from one source or another. During the same period, 115 (13.6%) of 844 positive tissue samples taken during surgery grew Staphylococcus aureus. Of these only 1 (0.01%) was reported to be methicillin-resistant (MRSA). However, a total of 366 (43.4%) isolates from tissue samples were reported as coagulase-negative staphylococci (C-NS). Of these, 312 samples were tested for methicillin sensitivity, of which 172 (55.1%) were found to be resistant. Staphylococcus epidermidis is the most prevalent and persistent species found on most skin and mucous membranes, constituting 65% to 90% of all staphylococci. Most isolates in tissue samples were found to be methicillin-resistant coagulase-negative staphylococcus (55.1%). Hence, it may be appropriate to undertake screening for methicillin-resistant Staphylococcus epidermidis in addition to that for MRSA.
一项对耐甲氧西林金黄色葡萄球菌（MRSA）筛查的回顾性研究表明，在1996年5月至2001年2月期间术前接受筛查的总共8911名患者中，有83名（0.9%）从一个或多个来源分离出了MRSA。在同一时期，手术期间采集的844份阳性组织样本中有115份（13.6%）培养出金黄色葡萄球菌。其中只有1份（0.01%）被报告为耐甲氧西林（MRSA）。然而，来自组织样本的总共366份（43.4%）分离株被报告为凝固酶阴性葡萄球菌（C-NS）。其中，312份样本进行了甲氧西林敏感性测试，其中172份（55.1%）被发现耐药。表皮葡萄球菌是在大多数皮肤和粘膜上发现的最普遍和持续存在的菌种，占所有葡萄球菌的65%至90%。组织样本中的大多数分离株被发现是耐甲氧西林凝固酶阴性葡萄球菌（55.1%）。因此，除了对MRSA进行筛查外，对耐甲氧西林表皮葡萄球菌进行筛查可能也是合适的。
