Segura Huerta A, Molina Saera J, Palomar Abad L, Pellín Ariño L, Guerrero Zotano A, Calderero Aragón V
Servicio de Oncología Médica, Hospital La Fe, Valencia.
Actas Urol Esp. 2004 Jan;28(1):57-61. doi: 10.1016/s0210-4806(04)73037-5.
Urethral cancer is an uncommon tumor (<0.1% of all genitourinary neoplasms). Most of them are squamous carcinoma, adenocarcinomas are about 5% of all urethral cancer. Surgery is the only curative treatment. Surgical technics depend of tumoral location and extension. Conservative surgery is elective if survival is not compromised. Extensive surgery is needed in large lesions. Chemotherapy (CT) and radiotherapy (RT) must be used in patients in which surgery is not possible. Due to the low incidence of this neoplasm is not well established the best therapeutic approach. We present the case of a female (35 years old) with a diagnosis of urethral adenocarcinoma. The initial stage was IV due to non-regional lymph nodes metastases. Surgery was impossible and the patient received chemotherapy and radiotherapy. The patient achieved complete response with CT but a progression was observed in course of RT. The patient died due to systemic progression.
尿道癌是一种罕见的肿瘤（占所有泌尿生殖系统肿瘤的比例不到0.1%）。其中大多数是鳞状细胞癌，腺癌约占所有尿道癌的5%。手术是唯一的根治性治疗方法。手术技术取决于肿瘤的位置和范围。如果不影响生存率，可选择保守手术。对于较大的病变则需要进行广泛手术。对于无法进行手术的患者，必须使用化疗（CT）和放疗（RT）。由于这种肿瘤的发病率较低，最佳治疗方法尚未完全确立。我们报告一例35岁女性尿道腺癌患者。由于出现非区域淋巴结转移，初始分期为IV期。无法进行手术，患者接受了化疗和放疗。患者对化疗有完全反应，但在放疗过程中出现进展。患者因全身进展而死亡。
