Spencer Thomas J
Department of Pediatric Psychopharmacology, Massachusetts General Hospital, Department of Psychiatry, Harvard Medical School, Boston 02114, USA.
J Clin Psychiatry. 2004;65 Suppl 3:22-6.
Since attention-deficit/hyperactivity disorder (ADHD) is usually diagnosed in children, evidence from the studies of pharmacologic treatments for children with ADHD is used to inform pharmacologic treatment recommendations for adults. A large percentage of children diagnosed with ADHD have symptoms that persist into adolescence and adulthood. Evidence shows that pharmacologic treatments improve functional outcomes in children with ADHD, and studies using similar pharmacologic treatments show positive results in adults with ADHD. This article reviews the use of long-acting methylphenidate, mixed amphetamine salts, desipramine, monoamine oxidase inhibitors, bupropion, and atomoxetine in studies of children, adolescents, and adults with ADHD.
由于注意力缺陷多动障碍(ADHD)通常在儿童期被诊断出来,因此针对患有ADHD儿童的药物治疗研究证据被用于为成人的药物治疗建议提供参考。很大比例被诊断患有ADHD的儿童其症状会持续到青春期和成年期。证据表明,药物治疗可改善患有ADHD儿童的功能结局,并且使用类似药物治疗的研究在患有ADHD的成人中也显示出积极结果。本文综述了长效哌醋甲酯、混合苯丙胺盐、地昔帕明、单胺氧化酶抑制剂、安非他酮和托莫西汀在患有ADHD的儿童、青少年及成人研究中的应用。