Ruttkay-Nedecký I
Institute of Normal and Pathological Physiology, Slovak Academy of Sciences, Sienkiewiczova 1, 81371 Bratislava., Slovak Republic.
Physiol Res. 2004;53(2):143-7.
Electrocardiographic correlates of ventricular activation sequence were studied in 22 Macaca mulatta monkeys, aged 1-18 years, and 145 human subjects, aged 11-72 years, using the corrected orthogonal lead system of McFee-Parungao and the dipolar electrocardiotopographic (DECARTO) data presentation, where the time series of instantaneous spatial vectors are converted into time series of areas of activation on a spherical image surface enveloping the heart. Macaques had shorter ventricular activation time (61+/-11 vs. 97+/-11 ms) that could not be explained exclusively by their higher heart rate. Their DECARTO image of the resultant activation front occurred 10 ms after QRS onset (septal activation) identically with humans, but it attained a more anteriorly oriented maximum earlier than in humans (20 vs. 40 ms). The time course of the extent of the resultant activation front in old macaques (15-18 years) resembled to that observed in humans. On the average, female macaques had smaller DECARTO images of activation fronts throughout the QRS complex than males. This finding is in agreement with the known smaller QRS amplitudes in women than in men.
使用麦克菲 - 帕伦高校正正交导联系统和偶极心电图地形学（DECARTO）数据呈现方式，对22只年龄在1至18岁的恒河猴和145名年龄在11至72岁的人类受试者的心室激动序列的心电图相关性进行了研究。在该系统中，瞬时空间向量的时间序列被转换为包围心脏的球形图像表面上的激动区域时间序列。恒河猴的心室激动时间较短（61±11 vs. 97±11毫秒），这不能完全用其较高的心率来解释。它们的综合激动前沿的DECARTO图像在QRS波起始后10毫秒（间隔激动）出现，与人类相同，但它比人类更早地达到更向前的最大值（20毫秒对40毫秒）。老年恒河猴（15至18岁）综合激动前沿范围的时间进程与人类观察到的相似。平均而言，雌性恒河猴在整个QRS波群中激动前沿的DECARTO图像比雄性小。这一发现与已知的女性QRS波幅小于男性一致。
