Kwon Y, Roh Y
School of Mechanical Engineering, Kyungpook National University, Sankyukdong 1370, Bukgu, Daegu 702-701, South Korea.
Ultrasonics. 2004 Apr;42(1-9):409-11. doi: 10.1016/j.ultras.2004.01.039.
We developed SH (shear horizontal) surface acoustic wave (SAW) sensors to detect protein molecules in liquid solutions applying a particular antibody thin film on the delay line of transverse SAW devices. The antibody investigated was human-immuno-globulin G (HigG) to hold the antigens (anti-HigG) in the protein solution to be measured. The sensor showed stable response to the mass loading effects of the anti-HigG molecules with the sensitivity up to 10.8 ng/ml/Hz.
我们开发了剪切水平(SH)表面声波(SAW)传感器,通过在横向SAW器件的延迟线上施加特定的抗体薄膜来检测液体溶液中的蛋白质分子。所研究的抗体是人免疫球蛋白G(HigG),用于捕获待测蛋白质溶液中的抗原(抗HigG)。该传感器对抗HigG分子的质量负载效应表现出稳定的响应,灵敏度高达10.8 ng/ml/Hz。