Newhook Leigh A, Curtis Joseph, Hagerty Donna, Grant Marie, Paterson Andrew D, Crummel Cheryl, Bridger Tracey, Parfrey Patrick
Memorial University of Newfoundland, Medicine, St. John's, Newfoundland, Canada.
Diabetes Care. 2004 Apr;27(4):885-8. doi: 10.2337/diacare.27.4.885.
The aim of this study was to determine the incidence of type 1 diabetes among children aged 0-14 years in the Avalon Peninsula in the Canadian Province of Newfoundland.
This was a prospective cohort study of the incidence of childhood type 1 diabetes in children aged 0-14 years who were diagnosed with type 1 diabetes from 1987 to 2002 on the Avalon Peninsula. Identified case subjects during this time period were ascertained from several sources and verified using the capture-recapture technique. Data were obtained from the only pediatric diabetes treatment center for children living on the Avalon Peninsula.
Over the study period, 294 children aged 0-14 years from the Avalon Peninsula were diagnosed with type 1 diabetes. The incidence of type 1 diabetes in this population over the period 1987-2002 inclusive was 35.93 with a 95% CI of 31.82-40.03. The incidence over this period increased linearly at the rate of 1.25 per 100,000 individuals per year.
The Avalon Peninsula of Newfoundland has one of the highest incidences of type 1 diabetes reported worldwide. The incidence increased over the 16-year study period.
本研究旨在确定加拿大纽芬兰省阿瓦隆半岛0至14岁儿童中1型糖尿病的发病率。
这是一项对1987年至2002年在阿瓦隆半岛被诊断为1型糖尿病的0至14岁儿童中1型糖尿病发病率的前瞻性队列研究。在此期间确定的病例来自多个来源，并使用捕获-再捕获技术进行核实。数据来自阿瓦隆半岛唯一的儿童糖尿病治疗中心。
在研究期间，阿瓦隆半岛有294名0至14岁儿童被诊断为1型糖尿病。在1987年至2002年（含）期间，该人群中1型糖尿病的发病率为35.93，95%置信区间为31.82至40.03。在此期间，发病率以每年每10万人1.25的速度呈线性上升。
纽芬兰的阿瓦隆半岛是全球报告的1型糖尿病发病率最高的地区之一。在16年的研究期间发病率有所上升。
