甲状腺癌的皮肤表现：4例报告并文献复习
Cutaneous manifestations of thyroid cancer: a report of four cases and review of the literature.
作者信息
Alwaheeb S, Ghazarian D, Boerner S L, Asa S L
机构信息
Department of Pathology and Laboratory Medicine, University of Toronto, University Health Network and Toronto Medical Laboratories, Ontario M5G 2M9, Canada.
出版信息
J Clin Pathol. 2004 Apr;57(4):435-8. doi: 10.1136/jcp.2003.012922.
Abstract
Cutaneous metastases from thyroid carcinoma are rare. This report describes four cases of thyroid carcinoma metastatic to the skin. Two cases were medullary carcinoma and two were papillary thyroid carcinoma. In two cases, skin metastases were the presenting feature of the underlying thyroid carcinoma. Examination of the skin lesions by conventional light microscopy suggested the possibility of metastatic carcinoma and immunohistochemical tests confirmed the diagnosis. Subsequent investigations identified primary thyroid lesions. In two cases, the skin metastasis was the first evidence of the recurrence of known thyroid carcinoma. These cases identify a novel presentation of thyroid carcinoma.
摘要
甲状腺癌的皮肤转移罕见。本报告描述了4例甲状腺癌转移至皮肤的病例。2例为髓样癌，2例为乳头状甲状腺癌。在2例中，皮肤转移是潜在甲状腺癌的首发表现。通过传统光学显微镜检查皮肤病变提示有转移癌的可能，免疫组化检测确诊了诊断。随后的检查发现了原发性甲状腺病变。在2例中，皮肤转移是已知甲状腺癌复发的首个证据。这些病例确定了甲状腺癌的一种新表现形式。
相似文献
1
Cutaneous manifestations of thyroid cancer: a report of four cases and review of the literature.甲状腺癌的皮肤表现：4例报告并文献复习
J Clin Pathol. 2004 Apr;57(4):435-8. doi: 10.1136/jcp.2003.012922.
2
Thyroid carcinoma metastatic to the skin: a cutaneous manifestation of a widely disseminated malignancy.甲状腺癌转移至皮肤：一种广泛播散性恶性肿瘤的皮肤表现。
J Am Acad Dermatol. 1997 Apr;36(4):531-7. doi: 10.1016/s0190-9622(97)70239-1.
3
Four patients with cutaneous metastases from medullary thyroid cancer.四名患有甲状腺髓样癌皮肤转移的患者。
Thyroid. 2008 Aug;18(8):901-5. doi: 10.1089/thy.2007.0179.
4
Cutaneous metastasis from papillary carcinoma of the thyroid gland.甲状腺乳头状癌的皮肤转移
J Am Acad Dermatol. 1991 Aug;25(2 Pt 2):404-8. doi: 10.1016/0190-9622(91)70216-o.
5
Papillary and follicular thyroid carcinoma metastatic to the skin: a case report and review of the literature.甲状腺乳头状癌和滤泡状癌转移至皮肤：1例病例报告并文献复习
Thyroid. 1998 Nov;8(11):1045-50. doi: 10.1089/thy.1998.8.1045.
6
A nodule on the scalp as the first sign of extranodal disease in medullary thyroid carcinoma.头皮结节作为甲状腺髓样癌结外病变的首发症状。
Dermatol Online J. 2017 May 15;23(5):13030/qt5r8475br.
7
Cutaneous metastasis of medullary thyroid carcinoma as the initial manifestation of an otherwise limited malignancy: a case report.甲状腺髓样癌皮肤转移作为局限性恶性肿瘤的初始表现：一例报告
Am J Dermatopathol. 2011 Oct;33(7):716-8. doi: 10.1097/DAD.0b013e3181fd7ada.
8
Metastatic papillary carcinoma of the thyroid.甲状腺转移性乳头状癌。
J Cutan Pathol. 2004 Aug;31(7):509-12. doi: 10.1111/j.0303-6987.2004.00218.x.
9
Cutaneous metastasis from papillary carcinoma of the thyroid gland. Report of two cases.甲状腺乳头状癌的皮肤转移。两例报告。
J Am Acad Dermatol. 1984 Jun;10(6):988-92. doi: 10.1016/s0190-9622(84)80320-5.
10
Cutaneous metastasis of papillary thyroid carcinoma to the neck: a case report and review of the literature.甲状腺乳头状癌颈部皮肤转移：一例报告并文献复习
Dermatol Online J. 2014 Dec 13;21(2):13030/qt78v2d22d.
引用本文的文献
1
Breaking Boundaries: Thyroid Cancer's Skin-Deep Twist.突破界限：甲状腺癌与皮肤的深层关联
Indian J Otolaryngol Head Neck Surg. 2024 Dec;76(6):5902-5905. doi: 10.1007/s12070-024-04982-4. Epub 2024 Aug 28.
2
Dermatologic manifestations of thyroid disease: a literature review.甲状腺疾病的皮肤表现：文献综述。
Front Endocrinol (Lausanne). 2023 May 12;14:1167890. doi: 10.3389/fendo.2023.1167890. eCollection 2023.
3
Unusual Clinical Manifestations of Thyroid Carcinoma.甲状腺癌的不寻常临床表现
Cureus. 2023 Apr 12;15(4):e37474. doi: 10.7759/cureus.37474. eCollection 2023 Apr.
4
Cutaneous metastases from solid neoplasms - Literature review.皮肤转移瘤——文献综述。
An Bras Dermatol. 2023 Sep-Oct;98(5):571-579. doi: 10.1016/j.abd.2022.10.009. Epub 2023 May 2.
5
Late recurrence of papillary thyroid cancer from needle tract implantation after core needle biopsy: A case report.粗针活检后针道种植导致甲状腺乳头状癌迟发性复发：一例报告
World J Clin Cases. 2021 Jan 6;9(1):218-223. doi: 10.12998/wjcc.v9.i1.218.
6
Cutaneous Metastasis from Papillary Carcinoma of Thyroid.甲状腺乳头状癌的皮肤转移
Indian Dermatol Online J. 2019 Sep 26;11(1):126-127. doi: 10.4103/idoj.IDOJ_78_19. eCollection 2020 Jan-Feb.
7
Skin metastasis on the neck: an unusual presentation of recurrence of papillary thyroid carcinoma.颈部皮肤转移：甲状腺乳头状癌复发的一种不寻常表现。
Gland Surg. 2017 Oct;6(5):594-597. doi: 10.21037/gs.2017.07.12.
8
Metastatic papillary thyroid carcinoma to the nose: report and review of cutaneous metastases of papillary thyroid cancer.甲状腺乳头状癌转移至鼻部：甲状腺乳头状癌皮肤转移的病例报告及文献复习
Dermatol Pract Concept. 2015 Oct 31;5(4):7-11. doi: 10.5826/dpc.0504a03. eCollection 2015 Oct.
9
Unusual Thyroid Carcinoma Metastases: a Case Series and Literature Review.罕见甲状腺癌转移：病例系列报道及文献综述
Endocr Pathol. 2016 Mar;27(1):55-64. doi: 10.1007/s12022-015-9410-7.
10
Asynchronous cutaneous metastases of medullary thyroid carcinoma.甲状腺髓样癌的异步皮肤转移
South Asian J Cancer. 2015 Apr-Jun;4(2):103-4. doi: 10.4103/2278-330X.155707.
本文引用的文献
1
Thyroid transcription factor-1: a review.甲状腺转录因子-1：综述
Appl Immunohistochem Mol Morphol. 2002 Jun;10(2):97-102. doi: 10.1097/00129039-200206000-00001.
2
Hepatic metastases from the spindle cell variant of medullary thyroid carcinoma: report of a case with diagnosis by fine needle aspiration biopsy.甲状腺髓样癌梭形细胞变异型的肝转移：1例经细针穿刺活检确诊的病例报告
Acta Cytol. 2001 Nov-Dec;45(6):1022-6. doi: 10.1159/000328348.
3
Bone metastases from thyroid carcinoma: a histopathologic study with clinical correlates.甲状腺癌骨转移：一项具有临床相关性的组织病理学研究。
Arch Pathol Lab Med. 2000 Oct;124(10):1440-7. doi: 10.5858/2000-124-1440-BMFTC.
4
Thyroid transcription factor-1, thyroglobulin, cytokeratin 7, and cytokeratin 20 in thyroid neoplasms.甲状腺肿瘤中的甲状腺转录因子-1、甲状腺球蛋白、细胞角蛋白7和细胞角蛋白20
Appl Immunohistochem Mol Morphol. 2000 Sep;8(3):189-94. doi: 10.1097/00129039-200009000-00004.
5
Expression of thyroid transcription factor-1 (TTF-1) in human C cells and medullary thyroid carcinomas.甲状腺转录因子-1（TTF-1）在人C细胞和甲状腺髓样癌中的表达。
Hum Pathol. 2000 Mar;31(3):386-93. doi: 10.1016/s0046-8177(00)80255-5.
6
Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas.甲状腺转录因子-1是肺癌和甲状腺癌的标志物。
Adv Anat Pathol. 2000 Mar;7(2):123-7. doi: 10.1097/00125480-200007020-00007.
7
Occult papillary carcinoma of the thyroid gland with extensive osseous metastases--a case report with review of the literature.甲状腺隐匿性乳头状癌伴广泛骨转移——1例病例报告并文献复习
Pathol Res Pract. 1999;195(10):711-4; discussion 715-6. doi: 10.1016/S0344-0338(99)80065-X.
8
Papillary and follicular thyroid carcinoma metastatic to the skin: a case report and review of the literature.甲状腺乳头状癌和滤泡状癌转移至皮肤：1例病例报告并文献复习
Thyroid. 1998 Nov;8(11):1045-50. doi: 10.1089/thy.1998.8.1045.
9
An unusual case of papillary carcinoma of the thyroid with cutaneous and breast metastases only.仅伴有皮肤和乳腺转移的甲状腺乳头状癌罕见病例。
Eur J Endocrinol. 1997 Sep;137(3):267-9. doi: 10.1530/eje.0.1370267.
10
Multiple haemorrhagic brain metastases from papillary thyroid cancer.甲状腺乳头状癌的多发性出血性脑转移瘤。
Neuroradiology. 1997 Mar;39(3):198-202. doi: 10.1007/s002340050393.
Zotero 插件