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更新降低感染风险的层级体系:防止过渡到注射方式。

Updating the infection risk reduction hierarchy: preventing transition into injection.

作者信息

Vlahov David, Fuller Crystal M, Ompad Danielle C, Galea Sandro, Des Jarlais Don C

机构信息

Center for Urban Epidemiologic Studies, New York Academy of Medicine, 1216 Fifth Avenue, New York, NY 10029, USA.

出版信息

J Urban Health. 2004 Mar;81(1):14-9. doi: 10.1093/jurban/jth083.

DOI:10.1093/jurban/jth083
PMID:15047779
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3456135/
Abstract

Current approaches to prevention of blood-borne infections in injection drug users include referral to drug abuse treatment, access to sterile syringes, bleach disinfection of injection equipment, and education about not sharing equipment. However, rates of some blood-borne infections (e.g., hepatitis C virus) remain elevated among injection drug users, especially early after initiation into injection drug use. With lower infection rates in noninjectors and transition into injection drug use occurring most commonly among these noninjectors, prevention of transition into injection drug use as an additional step to reduce risk for acquisition and transmission of blood-borne infections merits closer attention.

摘要

目前针对注射吸毒者预防血源性感染的方法包括转介至药物滥用治疗机构、提供无菌注射器、对注射设备进行漂白剂消毒以及开展关于不共用设备的教育。然而,一些血源性感染(如丙型肝炎病毒)在注射吸毒者中的发生率仍然很高,尤其是在开始注射吸毒后的早期。非注射吸毒者的感染率较低,且向注射吸毒的转变最常发生在这些非注射吸毒者中,因此,将预防向注射吸毒的转变作为降低血源性感染获取和传播风险的额外措施,值得密切关注。

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本文引用的文献

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Hepatitis C incidence--a comparison between injection and noninjection drug users in New York City.丙型肝炎发病率——纽约市注射吸毒者与非注射吸毒者的比较。
J Urban Health. 2004 Mar;81(1):20-4. doi: 10.1093/jurban/jth084.
2
A randomized controlled trial of monetary incentives vs. outreach to enhance adherence to the hepatitis B vaccine series among injection drug users.一项关于货币激励与外展服务以提高注射吸毒者对乙肝疫苗系列接种依从性的随机对照试验。
Drug Alcohol Depend. 2003 Aug 20;71(2):127-31. doi: 10.1016/s0376-8716(03)00074-7.
3
Hepatitis C virus infection among noninjecting drug users in New York City.纽约市非注射吸毒者中的丙型肝炎病毒感染情况
J Med Virol. 2003 Jul;70(3):387-90. doi: 10.1002/jmv.10407.
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Variability in the incidence of human immunodeficiency virus, hepatitis B virus, and hepatitis C virus infection among young injecting drug users in New York City.纽约市年轻注射吸毒者中人类免疫缺陷病毒、乙型肝炎病毒和丙型肝炎病毒感染发生率的差异
Am J Epidemiol. 2003 Mar 1;157(5):467-71. doi: 10.1093/aje/kwf222.
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Drug injection among street youths in Montreal: predictors of initiation.蒙特利尔街头青少年中的药物注射行为:开始注射的预测因素
J Urban Health. 2003 Mar;80(1):92-105. doi: 10.1093/jurban/jtg092.
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Opportunities for prevention: hepatitis C prevalence and incidence in a cohort of young injection drug users.预防机会:一组年轻注射吸毒者中的丙型肝炎患病率和发病率
Hepatology. 2002 Sep;36(3):737-42. doi: 10.1053/jhep.2002.35065.
7
Risk of hepatitis C virus infection among young adult injection drug users who share injection equipment.共用注射器具的年轻成年注射吸毒者感染丙型肝炎病毒的风险。
Am J Epidemiol. 2002 Apr 1;155(7):645-53. doi: 10.1093/aje/155.7.645.
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High-risk behaviors associated with transition from illicit non-injection to injection drug use among adolescent and young adult drug users: a case-control study.青少年和青年吸毒者中与从非法非注射吸毒转变为注射吸毒相关的高危行为:一项病例对照研究。
Drug Alcohol Depend. 2002 Apr 1;66(2):189-98. doi: 10.1016/s0376-8716(01)00200-9.
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Factors associated with adolescent initiation of injection drug use.与青少年开始注射吸毒相关的因素。
Public Health Rep. 2001;116 Suppl 1(Suppl 1):136-45. doi: 10.1093/phr/116.S1.136.
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Using a jail-based survey to monitor HIV and risk behaviors among Seattle area injection drug users.利用基于监狱的调查来监测西雅图地区注射吸毒者中的艾滋病毒及风险行为。
J Urban Health. 2001 Jun;78(2):264-78. doi: 10.1093/jurban/78.2.264.