Phan K Luan, Wager Tor D, Taylor Stephan F, Liberzon Israel
Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, Michigan 48201, USA.
CNS Spectr. 2004 Apr;9(4):258-66. doi: 10.1017/s1092852900009196.
Neuroimaging studies with positron emission tomography and functional magnetic resonance imaging have begun to describe the functional neuroanatomy of human emotion. Taken separately, specific studies vary in task dimensions and in type(s) of emotion studied, and are limited by statistical power and sensitivity. By examining findings across studies in a meta-analysis, we sought to determine if common or segregated patterns of activations exist in different emotions and across various emotional tasks. We surveyed over 55 positron emission tomography and functional magnetic resonance imaging activation studies, which investigated emotion in healthy subjects. This paper will review observations in several regions of interest in limbic (eg, amygdala, anterior cingulate cortex) and paralimbic (eg, medial prefrontal cortex, insula) brain regions in emotional responding.
正电子发射断层扫描和功能磁共振成像的神经影像学研究已开始描述人类情绪的功能性神经解剖学。单独来看，具体研究在任务维度和所研究情绪的类型上存在差异，并且受到统计功效和敏感性的限制。通过在一项荟萃分析中审视各项研究的结果，我们试图确定在不同情绪以及各种情绪任务中是否存在共同或分离的激活模式。我们调查了55项以上正电子发射断层扫描和功能磁共振成像激活研究，这些研究对健康受试者的情绪进行了调查。本文将回顾在边缘（如杏仁核、前扣带回皮质）和边缘旁（如内侧前额叶皮质、脑岛）脑区的几个感兴趣区域中情绪反应的观察结果。
