Kunze W A, Shafton A D, Kemm R E, McKenzie J S
Department of Physiology, University of Melbourne, Parkville, Vic., Australia.
Brain Res. 1992 Jun 26;583(1-2):327-31. doi: 10.1016/s0006-8993(10)80044-7.
We present intracellular data which demonstrates a unique facilitatory centrifugal influence on the output cells of the olfactory bulb; the source being the lateral component of the nucleus of the horizontal limb of the diagonal band (HDB), part of the basal forebrain magnocellular complex. Damage to this facilitatory HDB influence may explain the loss of olfactory sensitivity seen early in Alzheimer's disease in which pathological changes occur in the basal forebrain.
我们展示了细胞内数据，这些数据证明了对嗅球输出细胞存在一种独特的促进性离心影响；其来源是斜角带水平支核（HDB）的外侧部分，它是基底前脑大细胞复合体的一部分。这种促进性的HDB影响受损可能解释了在阿尔茨海默病早期出现的嗅觉敏感性丧失，该病中基底前脑会发生病理变化。
