Malik M H A, Gray J, Kay P R
Centre for Hip Surgery, Wrightington Hospital, Hall Lane, WN6 9EP, Appley Bridge, Wigan, UK.
Int Orthop. 2004 Aug;28(4):211-3. doi: 10.1007/s00264-004-0556-z. Epub 2004 Mar 27.
The purpose of this study was to investigate whether the clinical variables of non-steroidal anti-inflammatory drugs (NSAID) usage and cigarette smoking are possibly linked to aseptic loosening around total hip arthroplasty (THA). We performed a retrospective review of the records and radiographs of 224 patients attending for follow-up at Wrightington Hospital between August 2002 and 2003 who had undergone THA. The following information was recorded: age, gender, primary and revision surgery details, radiographic parameters, smoking history and NSAID usage history. Logistic regression analysis was used to determine if there is any statistically significant association between NSAID usage or smoking habit and aseptic loosening. No such association was found.
本研究的目的是调查非甾体抗炎药（NSAID）使用和吸烟的临床变量是否可能与全髋关节置换术（THA）周围的无菌性松动有关。我们对2002年8月至2003年间在赖廷顿医院接受随访的224例行THA的患者的记录和X线片进行了回顾性分析。记录了以下信息：年龄、性别、初次手术和翻修手术细节、影像学参数、吸烟史和NSAID使用史。采用逻辑回归分析来确定NSAID使用或吸烟习惯与无菌性松动之间是否存在任何统计学上的显著关联。未发现此类关联。
