大量氯喹中毒：早期治疗和院前治疗的重要性

Massive chloroquine intoxication: importance of early treatment and pre-hospital treatment.

作者信息

Messant Irène, Jérémie Nicolas, Lenfant François, Freysz Marc

机构信息

Département d'Anesthésie Réanimation, SAMU 21-Hôpital Général, Rue Faubourg Raines, 21000 Dijon, France.

出版信息

Resuscitation. 2004 Mar;60(3):343-6. doi: 10.1016/j.resuscitation.2003.11.007.

DOI:10.1016/j.resuscitation.2003.11.007

PMID:15050768

Abstract

Chloroquine intoxication, despite therapeutic improvements, remains a potentially serious condition. We report a case of a 25-year-old patient, having ingested 10 g of chloroquine, a dose commonly considered to be lethal. Thanks to appropriate early medical treatment, this patient's outcome was favourable. To our knowledge, the literature contains no other report of survival of a patient after such an intake. This report emphasises the need to use a pre-designed medical care protocol to implement appropriate therapy as rapidly as possible.

摘要

尽管治疗方法有所改进，但氯喹中毒仍然是一种潜在的严重病症。我们报告了一例25岁患者，摄入了10克氯喹，这一剂量通常被认为是致命的。由于早期得到了恰当的治疗，该患者预后良好。据我们所知，文献中没有其他关于摄入如此剂量氯喹后患者存活的报道。本报告强调了需要使用预先设计的医疗护理方案，以便尽快实施恰当的治疗。