Saris W H M, Schrauwen P
Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University, Maastricht, The Netherlands.
Int J Obes Relat Metab Disord. 2004 Jun;28(6):759-65. doi: 10.1038/sj.ijo.0802631.
Exercise has been proposed as a tool for the prevention of obesity. Apart from an effect on energy expenditure, in particular low-intensity (LI) exercise might also influence substrate metabolism in favour of fat oxidation. It is however unclear what is the most beneficial exercise regime for obese people. We therefore studied the effect of either high-intensity (HI) or LI exercise on 24 h energy expenditure (24 h EE) and substrate metabolism.
Eight healthy obese male volunteers (age: 38+/-1 y, BMI: 31+/-1 kg/m(2), W(max): 235+/-16 W) stayed in the respiration chamber for two nights and the day in-between. In the chamber they cycled either at a HI (three times 30 min in a interval protocol (2.5 min 80/50% W(max))) or LI (three times 60 min continuously at 38% W(max)) protocol with an equicaloric energy expenditure. In the chamber subjects were fed in energy balance (37/48/15% of energy as fat/carbohydrate/protein).
The 24 h EE was not significantly different between protocols. In both protocols, sleeping metabolic rate (SMR) was elevated after the exercise (average+6.7%). The 24 h respiratory quotient (24 h RQ) was not different between protocols. During exercise, RQ was higher in the HI compared to the LI protocol (0.93 vs 0.91 resp., P<0.05), whereas in the postexercise period RQ tended to be lower in the HI compared to the LI protocol (P=0.06).
24 h EE is not differently affected by HI or LI exercise in obese men. Similarly, the differences in HI and LI exercise, RQ are compensated postexercise leading to similar substrate oxidation patterns over 24 h independently of the level of exercise intensity.
运动已被提议作为预防肥胖的一种手段。除了对能量消耗有影响外，特别是低强度（LI）运动可能还会影响底物代谢，有利于脂肪氧化。然而，目前尚不清楚对肥胖人群最有益的运动方式是什么。因此，我们研究了高强度（HI）或低强度运动对24小时能量消耗（24 h EE）和底物代谢的影响。
八名健康的肥胖男性志愿者（年龄：38±1岁，体重指数：31±1 kg/m²，最大功率：235±16 W）在呼吸室内停留两晚及中间的一天。在室内，他们按照等热量能量消耗的方案，以高强度（采用间歇方案，三次30分钟，每次2.5分钟，功率为最大功率的80/50%）或低强度（连续三次60分钟，功率为最大功率的38%）进行骑行。在室内，受试者按照能量平衡状态进食（能量的37/48/15%分别为脂肪/碳水化合物/蛋白质）。
两种方案之间的24小时能量消耗没有显著差异。在两种方案中，运动后睡眠代谢率（SMR）均有所升高（平均升高6.7%）。两种方案之间的24小时呼吸商（24 h RQ）没有差异。运动期间，高强度方案的呼吸商高于低强度方案（分别为0.93和0.91，P<0.05），而在运动后期间，高强度方案的呼吸商相比于低强度方案有降低的趋势（P=0.06）。
肥胖男性的24小时能量消耗不受高强度或低强度运动的不同影响。同样，高强度和低强度运动在呼吸商方面的差异在运动后得到补偿，导致24小时内底物氧化模式相似，与运动强度水平无关。
