Ding Lian-An, Li Jie-Shou
Department of Medical Surgery, Affiliated Hospital of Qingdao University Medical School, 16 Jiangsu Road, Qingdao 266003, Shandong Province, China.
World J Gastroenterol. 2004 Apr 1;10(7):930-3. doi: 10.3748/wjg.v10.i7.930.
There are two main functions of gastrointestinal tract, digestion and absorption, and barrier function. The latter has an important defensive effect, which keeps the body away from the invading and damaging of bacteria and endotoxin. It maintains the systemic homeostasis. Intestinal dysfunction would happen when body suffers from diseases or harmful stimulations. The lesser dysfunction of GI tract manifests only disorder of digestion and absorption, whereas the more serious intestinal disorders would harm the intestinal protective mechanism, or intestinal barrier function, and bacterial/endotoxin translocation, of intestinal failure (IF) would ensue. This review discussed the theory of the intestinal failure, aiming at attracting recognition and valuable comments by clinicians.
胃肠道有两个主要功能，即消化吸收和屏障功能。后者具有重要的防御作用，可使机体免受细菌和内毒素的侵袭与损害，维持全身内环境稳定。当机体遭受疾病或有害刺激时，肠道功能会发生障碍。胃肠道功能轻度障碍仅表现为消化吸收紊乱，而较严重的肠道功能障碍会损害肠道保护机制，即肠道屏障功能，继而导致细菌/内毒素移位，引发肠衰竭（IF）。本文综述了肠衰竭理论，旨在引起临床医生的重视并获得宝贵意见。
