Kublik Ewa, Swiejkowski Daniel A, Wróbel Andrzej
Department of Neurophysiology, Nencki Institute of Experimental Biology, 3 Pasteur St., 02-093 Warsaw, Poland.
Acta Neurobiol Exp (Wars). 2003;63(4):377-82. doi: 10.55782/ane-2003-1477.
In order to elucidate the role of cortical input on sensory information processing in different thalamic somatosensory nuclei we recorded potentials evoked (EPs) by whisker deflections of short duration from ventral posteromedial (VPm) and medial posterior (POm) nuclei while manipulating cortico-thalamic activity by means of local cooling, lidocaine application or electrical stimulation. It appeared that only the earliest sub-component of the first negative wave of the EPs resulted from peripheral input, while the rest of the potential's negativity depended on cortical feedback. The latencies and amplitudes of EPs recorded at both nuclei were not significantly different, which might be attributed to urethane anesthesia.
为了阐明皮质输入在不同丘脑体感核团感觉信息处理中的作用，我们在通过局部冷却、利多卡因应用或电刺激来操纵皮质-丘脑活动的同时，记录了短持续时间的触须偏转在腹后内侧核（VPm）和后内侧核（POm）诱发的电位（EPs）。似乎只有EPs第一个负波的最早子成分来自外周输入，而电位的其余负性部分则依赖于皮质反馈。在两个核团记录的EPs的潜伏期和振幅没有显著差异，这可能归因于氨基甲酸乙酯麻醉。
