Sang F C, Kangethe S K, Orinda V A, Gatheru Z, Black R E, Waiyaki P G
Centre for Microbiology Research, Kenya Medical Research Institute.
East Afr Med J. 1992 Mar;69(3):135-9.
Three hundred and three children under 5 years old with acute measles and diarrhoea (cases) and 300 other age-matched children with diarrhoea (controls) were examined for enteroadherent E. coli (EAEC) and other agents including rotavirus and Cryptosporidium. EAEC was determined by tissue culture of HEP-2 cells. Other agents were determined by conventional methods. EAEC was identified from both cases and control accounting for 10.3% (31/303) and 15.2% (46/300) respectively. Other bacterial agents were: 10.3% (31/303) from cases and 12.8% (39/300) from controls. A higher detection rate of enteroparasites was found among cases 15% (45/300) than controls 8.9% (27/300) whereas rotavirus was the reverse, 3% (9/303) in cases and 30.3% (92/300) in controls. To our knowledge characterization of EAEC has not been done before and therefore might be attributing factor to some of our unexplained diarrhoeal cases.
对303名5岁以下患有急性麻疹和腹泻的儿童(病例组)以及300名其他年龄匹配的腹泻儿童(对照组)进行了肠黏附性大肠杆菌(EAEC)及其他病原体检测,这些病原体包括轮状病毒和隐孢子虫。通过HEP - 2细胞的组织培养来测定EAEC。其他病原体采用常规方法测定。在病例组和对照组中均检测出了EAEC,分别占10.3%(31/303)和15.2%(46/300)。其他细菌性病原体在病例组中的检出率为10.3%(31/303),在对照组中的检出率为12.8%(39/300)。病例组中肠道寄生虫的检出率(15%,45/300)高于对照组(8.9%,27/300),而轮状病毒的检出情况则相反,病例组为3%(9/303),对照组为30.3%(92/300)。据我们所知,此前尚未对EAEC进行过特征描述,因此它可能是导致我们一些不明原因腹泻病例的因素。