在生长激素治疗期间是否应常规监测血清胰岛素样生长因子-I（IGF-I）浓度？ - Suppr | 超能文献

Should serum IGF-I concentrations be monitored routinely during growth hormone therapy?

作者信息

Papagianni Maria, Stanhope Richard

机构信息

Great Ormond Street Hospital for Children and The Middlesex Hospital (UCLH), London, UK.

出版信息

J Pediatr Endocrinol Metab. 2004 Feb;17(2):141-2. doi: 10.1515/jpem.2004.17.2.141.

DOI:10.1515/jpem.2004.17.2.141

Abstract

摘要

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1

Should serum IGF-I concentrations be monitored routinely during growth hormone therapy?在生长激素治疗期间是否应常规监测血清胰岛素样生长因子-I（IGF-I）浓度？

J Pediatr Endocrinol Metab. 2004 Feb;17(2):141-2. doi: 10.1515/jpem.2004.17.2.141.

2

Serum free insulin-like growth factor I (IGF-I), total IGF-I, and IGF-binding protein-3 concentrations in normal children and children with growth hormone deficiency.正常儿童和生长激素缺乏症儿童的血清游离胰岛素样生长因子I（IGF-I）、总IGF-I及IGF结合蛋白-3浓度

J Clin Endocrinol Metab. 1999 Jan;84(1):82-9. doi: 10.1210/jcem.84.1.5407.

3

Monitoring of growth hormone replacement therapy in adults, based on measurement of serum markers.基于血清标志物测量的成人生长激素替代疗法监测。

J Clin Endocrinol Metab. 1996 Apr;81(4):1371-7. doi: 10.1210/jcem.81.4.8636336.

4

Monitoring serum insulin-like growth factor-I (IGF-I), IGF binding protein-3 (IGFBP-3), IGF-I/IGFBP-3 molar ratio and leptin during growth hormone treatment for disordered growth.在生长激素治疗生长紊乱期间监测血清胰岛素样生长因子-I（IGF-I）、IGF结合蛋白-3（IGFBP-3）、IGF-I/IGFBP-3摩尔比和瘦素。

Clin Endocrinol (Oxf). 2000 Sep;53(3):329-36. doi: 10.1046/j.1365-2265.2000.01105.x.

5

Two weeks of daily injections and continuous infusion of recombinant human growth hormone (GH) in GH-deficient adults: I. Effects on insulin-like growth factor-I (IGF-I), GH and IGF binding proteins, and glucose homeostasis.对生长激素缺乏的成年人进行为期两周的重组人生长激素（GH）每日注射及持续输注：I. 对胰岛素样生长因子-I（IGF-I）、生长激素及IGF结合蛋白以及葡萄糖稳态的影响。

Metabolism. 1996 Mar;45(3):362-9. doi: 10.1016/s0026-0495(96)90292-9.

6

Combined growth hormone (GH) and insulin-like growth factor-I (IGF-I) treatment is more effective than GH or IGF-I alone at enhancing recovery from neonatal malnutrition in rats.联合使用生长激素（GH）和胰岛素样生长因子-I（IGF-I）进行治疗，在促进新生大鼠从营养不良中恢复方面，比单独使用GH或IGF-I更有效。

J Nutr. 1995 Nov;125(11):2773-86. doi: 10.1093/jn/125.11.2773.

7

Evaluation of free insulin-like growth factor-I measurement on the diagnosis and follow-up treatment of growth hormone-deficient adult patients.游离胰岛素样生长因子-I测定在生长激素缺乏成年患者诊断及随访治疗中的评估

Clin Endocrinol (Oxf). 1999 Apr;50(4):441-9. doi: 10.1046/j.1365-2265.1999.00677.x.

8

Developmental pattern of fetal growth hormone, insulin-like growth factor I, growth hormone binding protein and insulin-like growth factor binding protein-3.胎儿生长激素、胰岛素样生长因子I、生长激素结合蛋白及胰岛素样生长因子结合蛋白-3的发育模式

Arch Dis Child Fetal Neonatal Ed. 1997 Sep;77(2):F100-4. doi: 10.1136/fn.77.2.f100.

9

Serum growth hormone (GH) binding protein, IGF-I and IGFBP-3 in patients with beta-thalassaemia major and the effect of GH treatment.重型β地中海贫血患者的血清生长激素（GH）结合蛋白、胰岛素样生长因子-I（IGF-I）和胰岛素样生长因子结合蛋白-3（IGFBP-3）以及生长激素治疗的效果。

Clin Endocrinol (Oxf). 1998 May;48(5):641-6. doi: 10.1046/j.1365-2265.1998.00470.x.

10

A switch from oral (2 mg/day) to transdermal (50 microg/day) 17beta-estradiol therapy increases serum insulin-like growth factor-I levels in recombinant human growth hormone (GH)-substituted women with GH deficiency.从口服（2毫克/天）转为经皮（50微克/天）17β-雌二醇治疗，可提高生长激素（GH）替代治疗的生长激素缺乏女性患者的血清胰岛素样生长因子-I水平。

J Clin Endocrinol Metab. 2000 Jan;85(1):464-7. doi: 10.1210/jcem.85.1.6311.

引用本文的文献

1

The growth hormone/IGF-1 axis is a risk factor for long-term kidney allograft failure.生长激素/胰岛素样生长因子-1轴是长期肾移植失败的一个危险因素。

JCI Insight. 2025 May 6;10(11). doi: 10.1172/jci.insight.188485. eCollection 2025 Jun 9.

2

Combined evaluation of IGF-1 and IGFBP-3 as an index of efficacy and safety in growth hormone treated patients.联合评估胰岛素样生长因子-1（IGF-1）和胰岛素样生长因子结合蛋白-3（IGFBP-3）作为生长激素治疗患者疗效和安全性指标的情况。

J Clin Res Pediatr Endocrinol. 2009;1(5):240-3. doi: 10.4274/jcrpe.v1i5.240. Epub 2009 Aug 5.