Baldi Bruno Guedes, Santana Alfredo Nicodemos Cruz, Takagaki Teresa Yae
Pulmonology Department, Faculdade de Medicina, Universidade de São Paulo, SaoPaulo, Brazil.
J Bras Pneumol. 2006 Nov-Dec;32(6):592-5. doi: 10.1590/s1806-37132006000600019.
Nocardiosis is a localized or disseminated infection caused by gram-positive bacteria of the genus Nocardia. The infection most commonly affects the lungs, skin and central nervous system. Nocardiosis principally occurs in individuals with cellular immunodeficiency and should be considered in the differential diagnosis when such individuals present respiratory, cutaneous or neurological alterations. Herein, we report a case of pulmonary and cutaneous nocardiosis in a patient receiving oral corticosteroids to treat bronchiolitis obliterans accompanied by organizing pneumonia of unknown origin. After long-term treatment with sulfamethoxazole-trimethoprim, the clinical and radiological profile improved.
诺卡菌病是由诺卡菌属革兰氏阳性菌引起的局部或播散性感染。该感染最常累及肺部、皮肤和中枢神经系统。诺卡菌病主要发生在细胞免疫缺陷的个体中,当这些个体出现呼吸、皮肤或神经改变时,应在鉴别诊断中考虑该病。在此,我们报告一例接受口服皮质类固醇治疗不明原因的闭塞性细支气管炎伴机化性肺炎的患者发生肺和皮肤诺卡菌病的病例。经过磺胺甲恶唑-甲氧苄啶长期治疗后,临床和影像学表现有所改善。