Viglizzo Gianmaria, Verrini Anna, Rongioletti Franco
Department of Endocrinologic and Metabolic Diseases, University of Genoa, Genoa, Italy.
Dermatology. 2004;208(2):142-4. doi: 10.1159/000076489.
Lassueur-Graham-Little-Piccardi syndrome (LGLPS) is a rare lichenoid dermatosis characterized by progressive cicatricial alopecia of the scalp, loss of pubic and axillary hairs and keratosis pilaris. The syndrome is considered a form of follicular lichen planus (LP). Although the familial occurrence of LP is a well-described phenomenon, no familial case of LGLPS has ever been reported. We describe the occurrence of LGLPS in a mother and her daughter. HLA typing revealed HLA-DR1 in both patients. Topical tacrolimus was of partial benefit in the daughter.
拉叙厄尔-格雷厄姆-利特尔-皮卡迪综合征（LGLPS）是一种罕见的苔藓样皮肤病，其特征为头皮进行性瘢痕性脱发、阴毛和腋毛脱落以及毛发角化病。该综合征被认为是扁平苔藓（LP）的一种形式。虽然LP的家族性发病是一种已被充分描述的现象，但从未有过LGLPS家族病例的报道。我们描述了一位母亲和她女儿发生LGLPS的情况。HLA分型显示两名患者均为HLA-DR1。外用他克莫司对女儿有部分疗效。
