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链霉菌属菌株C/33-6产生的一种蛋白质类化合物对产毒真菌的生长抑制作用

Growth inhibition of toxigenic fungi by a proteinaceous compound from Streptomyces sp. C/33-6.

作者信息

Fulgueira Cecilia L, Amigot Susana L, Magni Christian

机构信息

Centro de Referencia de Micología (CEREMIC), Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, 2000 Rosario, Argentina.

出版信息

Curr Microbiol. 2004 Feb;48(2):135-9. doi: 10.1007/s00284-003-4128-z.

Abstract

A Streptomyces sp. strain named C/33-6, previously isolated from soil, presented a strong and specific antagonistic effect against toxigenic fungi. This action was attributed to a proteinaceous compound (molecular weight estimated to be 14 kDa) present in the supernatant of the culture of strain C/33-6, which was sensitive to proteinases (elastase, pronase E, proteinase K) and prolongated heat treatment (100 degrees C, for 20 min). This compound showed non-chitinolytic fungicidal activity.

摘要

一种名为C/33 - 6的链霉菌菌株,先前从土壤中分离得到,对产毒真菌表现出强烈且特异的拮抗作用。这种作用归因于C/33 - 6菌株培养上清液中存在的一种蛋白质类化合物(估计分子量为14 kDa),该化合物对蛋白酶(弹性蛋白酶、链霉蛋白酶E、蛋白酶K)和长时间热处理(100℃,20分钟)敏感。这种化合物具有非几丁质分解性杀真菌活性。

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