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前海马体在关系记忆中的关键作用:来自一项比较联想和项目识别的功能磁共振成像研究的证据。

A critical role for the anterior hippocampus in relational memory: evidence from an fMRI study comparing associative and item recognition.

作者信息

Giovanello Kelly Sullivan, Schnyer David M, Verfaellie Mieke

机构信息

Memory Disorders Research Center, Boston VA Healthcare System and Boston University School of Medicine, Boston, Massachusetts 02130-4817, USA.

出版信息

Hippocampus. 2004;14(1):5-8. doi: 10.1002/hipo.10182.

DOI:10.1002/hipo.10182
PMID:15058477
Abstract

Neuroscientific research has established that the hippocampal formation, a structure within the medial temporal lobe (MTL), plays a critical role in memory for facts and events (declarative memory) (Milner et al., 1998). However, its precise role remains unclear. According to one view, the hippocampus has a special role in relating or binding together previously unrelated pieces of information, while another view proposes that the hippocampus is equally involved in all forms of declarative memory, regardless of their demands on relational processing. Using functional magnetic resonance imaging (fMRI), we show that hippocampal activation is modulated by the extent to which a retrieval task depends on relational processing.

摘要

神经科学研究已经证实,海马结构作为内侧颞叶(MTL)中的一个结构,在事实和事件记忆(陈述性记忆)中起着关键作用(米尔纳等人,1998年)。然而,其确切作用仍不清楚。一种观点认为,海马体在关联或整合先前不相关的信息片段方面具有特殊作用,而另一种观点则认为,海马体同样参与所有形式的陈述性记忆,无论它们对关系处理的要求如何。通过功能磁共振成像(fMRI),我们表明海马体激活受检索任务依赖关系处理程度的调节。

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