果蝇作为一种新兴的转移研究模型。
Drosophila as an emerging model to study metastasis.
作者信息
Kango-Singh Madhuri, Halder Georg
机构信息
Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
出版信息
Genome Biol. 2004;5(4):216. doi: 10.1186/gb-2004-5-4-216. Epub 2004 Mar 25.
Abstract
Metastasis is the primary cause of human cancer-related deaths. Two recent studies describe a system for testing how multiple genetic events synergize to promote neoplastic growth and metastasis in Drosophila, paving the way for systematic approaches to understanding metastasis using the powerful tools of Drosophila genetics.
摘要
转移是人类癌症相关死亡的主要原因。最近的两项研究描述了一种系统，用于测试多种基因事件如何协同作用以促进果蝇的肿瘤生长和转移，这为利用果蝇遗传学的强大工具来系统地理解转移铺平了道路。
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