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外照射与腔内照射联合用于食管癌根治性治疗的评估。

Evaluation of radical treatment of carcinoma esophagus using a combination of external beam and intracavitary irradiation.

作者信息

Sur R K, Kochhar R, Singh D P, Sharma S C, Goenka M K, Negi P S, Gupta B D, Mehta S K

机构信息

Department of Gastroenterology, Post-Graduate Institute of Medical Education and Research, Chandigarh.

出版信息

Indian J Gastroenterol. 1992 Jul;11(3):121-3.

PMID:1506047
Abstract

Twenty five patients with squamous cell carcinoma arising from the middle third of the esophagus were treated radically, with external radiation, to a dose of 55-60 Gy. All patients had lesions less than 6 cm in length with no extra-esophageal spread on computed tomography scan. Eleven of these patients received additional intracavitary radiation to a dose of 12 Gy, 1 cm from the source axis in two sessions of 6 Gy each, a week apart. There was no significant difference in the relief of dysphagia and survival among these receiving and those not receiving intracavitary radiation. Addition of intracavitary radiation to radical external radiation was associated with significant complications like stricture and fistulae formation, which accounted for the poor results.

摘要

25例食管中段鳞状细胞癌患者接受了根治性外照射,剂量为55 - 60 Gy。所有患者病变长度均小于6 cm,计算机断层扫描显示无食管外扩散。其中11例患者接受了额外的腔内照射,剂量为12 Gy,距源轴1 cm,分两次给予,每次6 Gy,间隔一周。接受腔内照射和未接受腔内照射的患者在吞咽困难缓解和生存方面无显著差异。在根治性外照射基础上增加腔内照射会出现诸如狭窄和瘘管形成等严重并发症,这导致了不良结果。

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