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用近距离放射疗法和迪德科特扩张器缓解食管癌

Palliation of carcinoma of the oesophagus with brachytherapy and the Didcott dilator.

作者信息

Sur R K, Didcott C C, Levin C V, Kulhavy M, Donde B, Schafer M, Gavenescu J

机构信息

Department of Radiation Oncology, University of the Witwatersrand, Johannesburg, South Africa.

出版信息

Ann R Coll Surg Engl. 1996 Mar;78(2):124-8.

Abstract

Forty-one patients with oesophageal cancer who developed strictures after high dose rate intraluminal brachytherapy were dilated using a slow continuous dilator (Didcott dilator). After dilatation, all patients were evaluated monthly for relief of dysphagia. At the end of the 1st month, 41 patients were evaluable: 28 had no dysphagia while 13 had improvement; at the end of the 2nd month, 40 were evaluable, 26 had no dysphagia while 14 had improvement; at the end of the 3rd month, 34 patients were evaluable, 24 had no dysphagia while 10 had improved. Three patients developed worsening of dysphagia owing to tumour recurrence among 32 patients who were evaluable at the end of the 4th month. Five patients developed worsening of dysphagia among the 26 patients who were evaluable at the 5th month due to tumour. These patients were dilated with the Didcott dilator and were treated with further brachytherapy. At the end of the 6th month, 14 patients were evaluable; seven had no dysphagia, while seven had improvement over their presenting dysphagia scores. Slow continuous dilatation using the Didcott dilator is very effective in the dilatation of strictures after high dose rate intraluminal brachytherapy. Dilatation is prolonged and sustained and a single dilatation is usually enough to maintain patency.

摘要

41例食管癌患者在高剂量率腔内近距离放疗后出现狭窄,使用慢速连续扩张器(迪德科特扩张器)进行扩张。扩张后,每月对所有患者进行吞咽困难缓解情况评估。第1个月末,41例患者可评估:28例无吞咽困难,13例有所改善;第2个月末,40例可评估,26例无吞咽困难,14例有所改善;第3个月末,34例患者可评估,24例无吞咽困难,10例有所改善。在第4个月末可评估的32例患者中,3例因肿瘤复发出现吞咽困难加重。在第5个月末可评估的26例患者中,5例因肿瘤出现吞咽困难加重。这些患者用迪德科特扩张器进行扩张,并接受进一步的近距离放疗。第6个月末,14例患者可评估;7例无吞咽困难,7例较其初始吞咽困难评分有所改善。使用迪德科特扩张器进行慢速连续扩张在高剂量率腔内近距离放疗后狭窄的扩张中非常有效。扩张过程延长且持续,单次扩张通常足以维持通畅。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5fa/2502532/b1692be3eb77/annrcse01600-0055-a.jpg

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