Withaferin-'A'与氢化可的松对四氯化碳诱导的大鼠肝毒性的保护作用比较。
Comparison of the protective effect of Withaferin-'A' and hydrocortisone against CCL4 induced hepatotoxicity in rats.
作者信息
Sudhir S, Budhiraja R D
机构信息
Department of Pharmacology, Medical College, Rohtak.
出版信息
Indian J Physiol Pharmacol. 1992 Apr;36(2):127-9.
PMID:1506077
Abstract
Protective effect of Withaferin-'A' against CCl4 induced hepatotoxicity has been assessed and the compound at 10 mg/kg dose was found to possess significant protective effect. A comparison of this protective effect with that of hydrocortisone showed it to be as effective as hydrocortisone dose per dose.
摘要
已评估了 Withaferin - 'A' 对四氯化碳诱导的肝毒性的保护作用，发现 10 mg/kg 剂量的该化合物具有显著的保护作用。将这种保护作用与氢化可的松的保护作用进行比较，结果表明其每剂量的效果与氢化可的松一样有效。
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