Han Chun-Mao, Shao Hua-Wei, He Xiao-Jie, Wang Lian-Cong
Department of Burns, Second Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310009, China.
Zhonghua Wai Ke Za Zhi. 2004 Mar 7;42(5):288-90.
To explore the effectiveness of postoperative electron beam irradiation therapy for keloid.
Forty-eight patients with 65 keloid sites were treated by surgical removal and postoperative 25 Gy electron beam irradiation from 1994 to 2002 and followed for over eighteen months. Statistical analysis was performed and therapeutic outcome was evaluated.
The overall recurrence rate was 26%. Higher post-treatment recurrence rates were noted with keloid forming at infected sites and in patients with family history (47.8% and 53.3%) (P < 0.05). Meanwhile, patient age, sex, keloid size and location had no increased likehood of recurrence rate.
The study shows that postoperative electron beam irradiation therapy is a kind of safe and effective method in inhibiting recurrence of keloid formation and eradicating it.
探讨术后电子束照射治疗瘢痕疙瘩的有效性。
1994年至2002年，对48例患者的65个瘢痕疙瘩部位进行手术切除，并在术后给予25 Gy电子束照射，随访超过18个月。进行统计学分析并评估治疗效果。
总复发率为26%。感染部位形成瘢痕疙瘩的患者和有家族史的患者治疗后复发率较高（分别为47.8%和53.3%）（P<0.05）。同时，患者的年龄、性别、瘢痕疙瘩大小和位置并未增加复发率。
研究表明，术后电子束照射治疗是一种安全有效的抑制瘢痕疙瘩形成复发并根除瘢痕疙瘩的方法。
