Ng Y K, Wong W C, Ling E A
Department of Anatomy, National University of Singapore.
J Anat. 1992 Apr;180 ( Pt 2)(Pt 2):305-14.
The structure of the intraglandular submandibular ganglion is described in both postnatal and adult rats. The ganglion is localised mainly at the hilum where the majority of the cell bodies are observed. Ganglia are also present in the intralobular septa of both the submandibular and the sublingual glands. Often they are found along the main salivary ducts with the larger ganglia being encapsulated by connective tissue. On electron microscopy, the submandibular ganglion cells show the usual features of autonomic neurons. The cells contain a prominent round nucleus. Numerous short processes project from the soma together with a few long dendrites. The organelles are randomly distributed throughout the soma. Most of the synapses observed were on the short processes with occasional axosomatic synapses. Nonsynaptic desmosome-like contacts are a common feature among the ganglion cells. Especially noteworthy are contacts made by the dendrites which deeply invaginate the soma of an adjacent nerve cell. The ganglion cells of the postnatal and adult submandibular ganglia show minor differences. Ultrastructurally, the postnatal cells show signs of immaturity such as abundant free ribosomes, well developed Golgi complexes and disorganised rough endoplasmic reticulum. Mitotic satellite cells were observed associated with the postnatal ganglion cells. The study has confirmed that all the submandibular ganglion cells show a positive reaction for acetylcholinesterase. Enzyme activity is localised in the cisternae of rough endoplasmic reticulum, the Golgi complex, plasma membrane and nuclear envelope.
本文描述了出生后和成年大鼠下颌下腺内神经节的结构。该神经节主要位于门部，此处可见大多数细胞体。在颌下腺和舌下腺的小叶间隔中也存在神经节。它们常沿着主要唾液腺导管分布，较大的神经节被结缔组织包裹。在电子显微镜下，下颌下神经节细胞显示出自主神经元的常见特征。细胞含有一个突出的圆形细胞核。许多短突起从胞体伸出，还有一些长树突。细胞器随机分布于整个胞体。观察到的大多数突触位于短突起上，偶尔也有轴-体突触。非突触性桥粒样接触是神经节细胞的共同特征。特别值得注意的是树突与相邻神经细胞胞体形成的深深内陷的接触。出生后和成年下颌下神经节的神经节细胞存在细微差异。在超微结构上，出生后的细胞显示出不成熟的迹象，如丰富的游离核糖体、发达的高尔基体和紊乱的粗面内质网。观察到有丝分裂卫星细胞与出生后的神经节细胞相关联。该研究证实，所有下颌下神经节细胞对乙酰胆碱酯酶均呈阳性反应。酶活性定位于粗面内质网池、高尔基体、质膜和核膜。
