Bottaro B, Cutler L S
Arch Oral Biol. 1984;29(3):237-42. doi: 10.1016/0003-9969(84)90061-x.
The development of the functional relationship between the autonomic nerves that regulate secretion and the acini of the gland (SMG) was studied. Electrophysiologic studies indicated that stimulation of the parasympathetic nerves at birth caused the secretion of fluid from the duct system but did not cause protein secretion from the developing acini or terminal tubules. Stimulation of the sympathetic innervation (superior cervical ganglion) did not cause protein secretion from developing acini or terminal tubules until 5 days after birth. The amount of protein released progressively increased in response to electrical stimulation of the cervical ganglion as the animals aged. This increased secretory response was correlated with the appearance of increasing numbers of catecholamine-containing neurones in the gland parenchyma.
研究了调节分泌的自主神经与腺体（下颌下腺）腺泡之间功能关系的发育情况。电生理研究表明，出生时刺激副交感神经会导致导管系统分泌液体，但不会导致发育中的腺泡或终末小管分泌蛋白质。刺激交感神经支配（颈上神经节）直到出生后5天才会导致发育中的腺泡或终末小管分泌蛋白质。随着动物年龄的增长，对颈神经节进行电刺激后释放的蛋白质量逐渐增加。这种分泌反应的增加与腺实质中含儿茶酚胺神经元数量的增加有关。
