Antioxidant properties of novel benzimidazole retinoids.
作者信息
Ates-Alagoz Zeynep, Can-Eke Benay, Coban Tulay, Iscan Mumtaz, Buyukbingol Erdem
机构信息
Department of Pharmaceutical Chemistry, Ankara University, Faculty of Pharmacy, Tandogan, Ankara, Turkey.
出版信息
Arch Pharm (Weinheim). 2004 Apr;337(4):188-92. doi: 10.1002/ardp.200300834.
PMID:15065077
Abstract
Our approach was to examine the antioxidant activity of novel retinoid derivatives containing the benzimidazole moiety. Their in vitro effects on rat liver microasomal, NADPH-dependent lipid peroxidation levels and superoxide anion formation were determined. Lipid peroxidation in rat liver microsomes was reduced by some of the compounds in a dose-dependent manner.
摘要
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