水和脯氨酸衍生的四氮唑催化剂辅助的不对称直接羟醛反应 - Suppr

Suppr

超能文献

Asymmetric direct aldol reaction assisted by water and a proline-derived tetrazole catalyst.

作者信息

Torii Hiromi, Nakadai Masakazu, Ishihara Kazuaki, Saito Susumu, Yamamoto Hisashi

机构信息

Graduate School of Engineering, Nagoya University, Chikusa, Nagoya 464-8603, Japan.

出版信息

Angew Chem Int Ed Engl. 2004 Apr 2;43(15):1983-6. doi: 10.1002/anie.200352724.

DOI:10.1002/anie.200352724

PMID:15065280

Abstract

摘要

相似文献

Asymmetric direct aldol reaction assisted by water and a proline-derived tetrazole catalyst.水和脯氨酸衍生的四氮唑催化剂辅助的不对称直接羟醛反应

Angew Chem Int Ed Engl. 2004 Apr 2;43(15):1983-6. doi: 10.1002/anie.200352724.

Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions.脯氨酸衍生物的有机催化：用于不对称曼尼希反应、硝基迈克尔反应和羟醛缩合反应的改进催化剂。

Org Biomol Chem. 2005 Jan 7;3(1):84-96. doi: 10.1039/b414742a. Epub 2004 Nov 29.

5-(Pyrrolidin-2-yl)tetrazole-catalyzed aldol and mannich reactions: acceleration and lower catalyst loading in a continuous-flow reactor.5-（吡咯烷-2-基）四唑催化的羟醛缩合反应和曼尼希反应：连续流动反应器中的加速作用及较低催化剂负载量

Angew Chem Int Ed Engl. 2009;48(15):2699-702. doi: 10.1002/anie.200804407.

Expedient synthesis of chiral 1,2- and 1,4-diamines: protecting group dependent regioselectivity in direct organocatalytic asymmetric Mannich reactions.手性1,2-和1,4-二胺的便捷合成：直接有机催化不对称曼尼希反应中保护基依赖性区域选择性

Org Lett. 2006 Jun 22;8(13):2839-42. doi: 10.1021/ol060980d.

Protonated N'-benzyl-N'-prolyl proline hydrazide as highly enantioselective catalyst for direct asymmetric aldol reaction.质子化的N'-苄基-N'-脯氨酰脯氨酸酰肼作为直接不对称羟醛反应的高对映选择性催化剂。

Chem Commun (Camb). 2006 Jan 14(2):215-7. doi: 10.1039/b511992h. Epub 2005 Nov 18.

Asymmetric organocatalytic direct aldol reactions of ketones with alpha-keto acids and their application to the synthesis of 2-hydroxy-gamma-butyrolactones.酮与α-酮酸的不对称有机催化直接羟醛反应及其在2-羟基-γ-丁内酯合成中的应用。

J Org Chem. 2007 Dec 21;72(26):9905-13. doi: 10.1021/jo701868t. Epub 2007 Nov 16.

5-(pyrrolidin-2-yl)-1H-tetrazole and 5-[(pyrrolidin-2-yl)methyl]-1H-tetrazole: proline surrogates with increased potential in asymmetric catalysis.5-（吡咯烷-2-基）-1H-四唑和5-［（吡咯烷-2-基）甲基］-1H-四唑：在不对称催化中具有更大潜力的脯氨酸替代物。

Chem Biodivers. 2006 Feb;3(2):119-33. doi: 10.1002/cbdv.200690016.

Direct asymmetric alpha-amination of cyclic ketones catalyzed by siloxyproline.硅氧基脯氨酸催化环状酮的直接不对称α-胺化反应

Chem Asian J. 2008 Feb 1;3(2):225-32. doi: 10.1002/asia.200700307.

Proline-tetrazole-catalyzed enantioselective N-nitroso aldol reaction of aldehydes with in situ generated nitrosocarbonyl compounds.脯氨酸-四唑催化的醛与原位生成的亚硝酰羰基金属化合物的对映选择性 N-亚硝基羟醛缩合反应。

Angew Chem Int Ed Engl. 2014 Aug 11;53(33):8714-7. doi: 10.1002/anie.201311069. Epub 2014 Feb 19.

A highly efficient organocatalyst for direct aldol reactions of ketones with aldehydes [corrected].一种用于酮与醛直接羟醛反应的高效有机催化剂[已修正]。

J Am Chem Soc. 2005 Jun 29;127(25):9285-9. doi: 10.1021/ja0510156.

引用本文的文献

Organocatalytic Packed-Bed Reactors for the Enantioselective Flow Synthesis of Quaternary Isotetronic Acids by Direct Aldol Reactions of Pyruvates.用于通过丙酮酸直接羟醛缩合反应对映选择性流动合成季碳异特窗酸的有机催化填充床反应器

Molecules. 2025 Jan 13;30(2):296. doi: 10.3390/molecules30020296.

Diastereoselective hydride transfer enables a synthesis of chiral 1,5-carboxamido-trifluoromethylcarbinols.非对映选择性氢化物转移反应可实现手性1,5-羧酰胺基三氟甲基甲醇的合成。

Chem Sci. 2024 Sep 9;15(38):15751-6. doi: 10.1039/d4sc05049e.

Catalytic Tetrazole Synthesis via [3+2] Cycloaddition of NaN to Organonitriles Promoted by Co(II)-complex: Isolation and Characterization of a Co(II)-diazido Intermediate.通过钴（II）配合物促进的NaN与有机腈的[3+2]环加成反应催化合成四唑：钴（II）-二叠氮化物中间体的分离与表征

ACS Omega. 2024 Apr 29;9(19):21626-21636. doi: 10.1021/acsomega.4c02567. eCollection 2024 May 14.

Evaluation of the enantioselectivity of new chiral ligands based on imidazolidin-4-one derivatives.基于咪唑烷-4-酮衍生物的新型手性配体对映选择性的评估。

Beilstein J Org Chem. 2024 Apr 2;20:684-691. doi: 10.3762/bjoc.20.62. eCollection 2024.

Asymmetric Organocatalyzed Transfer Hydroxymethylation of Isoindolinones Using Formaldehyde Surrogates.使用甲醛替代物实现异吲哚啉酮的不对称有机催化转移羟甲基化反应

Org Lett. 2024 Mar 29;26(12):2505-2510. doi: 10.1021/acs.orglett.4c00818. Epub 2024 Mar 19.

Enabling High Throughput Kinetic Experimentation by Using Flow as a Differential Kinetic Technique.通过将流动用作差分动力学技术实现高通量动力学实验。

Angew Chem Int Ed Engl. 2024 Jan 25;63(5):e202318146. doi: 10.1002/anie.202318146. Epub 2023 Dec 22.

Multiscale Modeling Approach for the Aldol Addition Reaction in Multicompartment Micelle-Based Nanoreactor.基于多隔室胶束的纳米反应器中羟醛加成反应的多尺度建模方法

J Phys Chem B. 2023 Nov 23;127(46):10067-10076. doi: 10.1021/acs.jpcb.3c05858. Epub 2023 Nov 13.

Biocompatible α-Methylenation of Metabolic Butyraldehyde in Living Bacteria.生物相容的代谢丁醛在活细菌中的α-亚甲基化。

Angew Chem Int Ed Engl. 2023 Sep 18;62(38):e202306347. doi: 10.1002/anie.202306347. Epub 2023 Aug 9.

Catalytically Active Multicompartment Micelles.具有催化活性的多室胶束

JACS Au. 2022 Sep 19;2(10):2316-2326. doi: 10.1021/jacsau.2c00367. eCollection 2022 Oct 24.

Synthesis and Stereochemical Characterization of a Novel Chiral α-Tetrazole Binaphthylazepine Organocatalyst.新型手性 α-四唑联萘并氮杂卓有机催化剂的合成与立体化学特征。

Molecules. 2022 Aug 11;27(16):5113. doi: 10.3390/molecules27165113.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验