Ketterer Mark W, Denollet Johan, Chapp Jeanine, Keteyian Steve, Farha A J, Clark Vivian, Hudson Michael, Hakim Arif, Greenbaum Adam, Schairer John, Cao J Jane
Heart & Vascular Institute, Henry Ford Health Sciences Center, Detroit, Michigan, USA.
J Behav Med. 2004 Feb;27(1):1-10. doi: 10.1023/b:jobm.0000013640.69802.fa.
In equal sized samples, a strong association between a positive Family History of Early Coronary Heart Disease (FamHx) and early Age at Initial Diagnosis (AAID) was found only for males, and thus all further analyses were restricted to males. All three scales of the self-report version of the Ketterer Stress Symptom Frequency Checklist--Revised (KSSFCR)--"AIAI" (or aggravation, irritation, anger, and impatience), Depression, and Anxiety--were associated with both a positive FamHx and early AAID. A series of regression models was used to demonstrate that the KSSFCR scales may plausibly account for 22-32% of the variance in the relationship between a positive FamHx and early AAID. Because of previously documented denial in males, the analyses were repeated in a subgroup of males for whom Spouse/Friend KSSFCRs were obtained. Spouse/Friend-reported AIAI was related to both early FamHx and early AAID, and could account for 68% of the common variance.
在样本量相等的情况下，仅在男性中发现早期冠心病家族史（FamHx）阳性与初次诊断时的早期年龄（AAID）之间存在强关联，因此所有进一步分析均限于男性。凯特勒压力症状频率清单修订版（KSSFCR）自我报告版本的所有三个量表——“AIAI”（即加重、易怒、愤怒和不耐烦）、抑郁和焦虑——均与FamHx阳性和早期AAID相关。一系列回归模型被用于证明KSSFCR量表可能合理地解释了FamHx阳性与早期AAID之间关系中22%至32%的方差。由于之前有文献记载男性存在否认现象，因此在获得配偶/朋友KSSFCR的男性亚组中重复了分析。配偶/朋友报告的AIAI与早期FamHx和早期AAID均相关，且可解释68%的共同方差。
