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生活在瑞士的青少年的哮喘、花粉热和特应性致敏情况未出现进一步增加。

No further increase in asthma, hay fever and atopic sensitisation in adolescents living in Switzerland.

作者信息

Braun-Fahrländer C, Gassner M, Grize L, Takken-Sahli K, Neu U, Stricker T, Varonier H S, Wüthrich B, Sennhauser F H

机构信息

Institute of Social and Preventive Medicine, University of Basel, Basel, Switzerland.

出版信息

Eur Respir J. 2004 Mar;23(3):407-13. doi: 10.1183/09031936.04.00074004.

Abstract

Prevalence rates of childhood asthma and allergy have been on the increase for several decades. The present study investigated whether this trend continued during the 1990s in adolescents living in Switzerland. Between 1992 and 2000, the change in prevalence of specific immunoglobulin E to aeroallergens, asthma symptoms and hay fever symptoms assessed by parents' and students' answers to the International Study of Asthma and Allergies in Childhood questions was investigated using three cross-sectional surveys. In total 1,324 (74.9%), 1,668 (80.6%) and 1,250 (73.9%) adolescents participated. Prevalence rates of asthma and current asthmatic symptoms remained constant, irrespective of whether the assessment was based on parental questionnaires or the student's self-completed written or video questionnaires (students' report of current wheeze 8.8, 7.3, and 8.3%). Similarly, no further increase was observed for reported hay fever rates and allergic sensitisation rates (positive multiscreen allergy test, SX1-test: 34.6, 38.9, and 35.6%, respectively). Although time trends in the occurrence of a series of known risk factors were recorded, none of these factors had a significant impact on asthma and allergy prevalence over time. No further increase in asthma and allergy rates occurred during the 1990s in adolescents living in Switzerland. However, to adequately assess the trend a longer period of observation is needed.

摘要

几十年来,儿童哮喘和过敏的患病率一直在上升。本研究调查了20世纪90年代生活在瑞士的青少年中这一趋势是否仍在持续。在1992年至2000年期间,利用三次横断面调查,通过家长和学生对儿童哮喘和过敏国际研究问题的回答,调查了针对空气过敏原的特异性免疫球蛋白E、哮喘症状和花粉症症状患病率的变化。共有1324名(74.9%)、1668名(80.6%)和1250名(73.9%)青少年参与。哮喘和当前哮喘症状的患病率保持不变,无论评估是基于家长问卷还是学生自行填写的书面或视频问卷(学生报告的当前喘息率分别为8.8%、7.3%和8.3%)。同样,报告的花粉症患病率和过敏致敏率(多重筛查过敏试验阳性,SX1试验:分别为34.6%、38.9%和35.6%)也没有进一步上升。尽管记录了一系列已知风险因素出现的时间趋势,但随着时间的推移,这些因素均未对哮喘和过敏患病率产生显著影响。20世纪90年代,生活在瑞士的青少年中哮喘和过敏率没有进一步上升。然而,要充分评估这一趋势,还需要更长的观察期。

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