Kasantikul V, Swasdikul D
Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
J Med Assoc Thai. 1992 Mar;75(3):184-9.
An 18-year-old woman had unusual clinical manifestations of malignant histiocytosis (MH) including a long duration of massive splenomegaly, absence of lymphadenopathy, and a number of exacerbations characterized by sudden onset of fever. During life, a definite diagnosis could not be established. The antemortem pathology of the marrow and liver was nonspecific and non-diagnostic. The diagnosis of MH was made after postmortem examination by histologic and immunohistochemical studies. The long duration of massive splenomegaly suggests that this patient could represent a chronic form of MH.
一名18岁女性患有恶性组织细胞增多症（MH）的不寻常临床表现，包括长期的巨脾肿大、无淋巴结病，以及多次以突然发热起病为特征的病情加重。生前未能确诊。骨髓和肝脏的生前病理学检查无特异性且无法诊断。死后经组织学和免疫组化研究确诊为MH。长期的巨脾肿大提示该患者可能代表MH的一种慢性形式。
