Shaabani Ahmad, Teimouri Mohammad Bagher, Bazgir Ayoob, Bijanzadeh Hamid Reza
Department of Chemistry, Shahid Beheshti University, 1983963113 Tehran, Iran.
Mol Divers. 2003;6(3-4):199-206. doi: 10.1023/b:modi.0000006759.20910.f1.
A novel four-component reaction approach to the efficient synthesis of triamide and amidodiester derivatives using amines or alcohols, aldehydes and alkyl or aryl isocyanides in the presence of Meldrum's acid as a CH acid, instead of carboxylic acid of Ugi four-component reaction, was studied.
研究了一种新型的四组分反应方法，该方法在丙二酸亚异丙酯作为碳氢酸存在的情况下，使用胺或醇、醛以及烷基或芳基异氰化物，以高效合成三酰胺和酰胺二酯衍生物，取代了乌吉四组分反应中的羧酸。
