• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

通过氨基酸(尤其是天冬氨酸)的外消旋作用从牙齿估计年龄——牙釉质和牙本质的比较。

Estimation of age from a tooth by means of racemization of an amino acid, especially aspartic acid--comparison of enamel and dentin.

作者信息

Ohtani S, Yamamoto K

机构信息

Department of Forensic Medicine, Kanagawa Dental College, Japan.

出版信息

J Forensic Sci. 1992 Jul;37(4):1061-7.

PMID:1506827
Abstract

In a study of age estimation from teeth by means of measuring racemization of aspartic acid (Asp), a representative amino acid, the accuracy of data from enamel and dentin in the same tooth was compared. The correlation of D/L ratio of aspartic acid with actual age gave the following parameters: r = 0.928, sigma = +/- 5.2, k = 4.47 x 10(-4) yr-1 in enamel and r = 0.995, sigma = +/- 1.4, k = 5.75 x 10(-4) yr-1. The difference in ages between one estimated by the D/L ratio and the actual one was within +/- 3 years in dentin, while in enamel an error of from 2 to 11 years was observed. Reaction rate constants of the racemization in a dry postmortem state (15 degrees C) were calculated as k = 9.70 x 10(-8) yr-1 in enamel, and k = 1.33 x 10(-7) yr-1 in dentin. Compared to rates determined from teeth recently extracted from living subjects, the rate was higher in dentin than in enamel. These data reconfirmed that dentin is superior to enamel in making exact age estimations from teeth.

摘要

在一项通过测量代表性氨基酸天冬氨酸(Asp)的消旋作用来从牙齿估计年龄的研究中,对同一颗牙齿牙釉质和牙本质数据的准确性进行了比较。天冬氨酸的D/L比率与实际年龄的相关性得出以下参数:在牙釉质中,r = 0.928,σ = ±5.2,k = 4.47×10⁻⁴ 年⁻¹;在牙本质中,r = 0.995,σ = ±1.4,k = 5.75×10⁻⁴ 年⁻¹。通过D/L比率估计的年龄与实际年龄之间的差异在牙本质中为±3岁以内,而在牙釉质中观察到的误差为2至11岁。在干燥的死后状态(15摄氏度)下消旋作用的反应速率常数计算得出:在牙釉质中k = 9.70×10⁻⁸ 年⁻¹,在牙本质中k = 1.33×10⁻⁷ 年⁻¹。与从活体近期拔除的牙齿所确定的速率相比,牙本质中的速率高于牙釉质中的速率。这些数据再次证实,在从牙齿进行精确年龄估计方面,牙本质优于牙釉质。

相似文献

1
Estimation of age from a tooth by means of racemization of an amino acid, especially aspartic acid--comparison of enamel and dentin.通过氨基酸(尤其是天冬氨酸)的外消旋作用从牙齿估计年龄——牙釉质和牙本质的比较。
J Forensic Sci. 1992 Jul;37(4):1061-7.
2
Studies on age estimation using racemization of aspartic acid in cementum.利用牙骨质中天冬氨酸消旋化进行年龄估计的研究。
J Forensic Sci. 1995 Sep;40(5):805-7.
3
[Age estimation by amino acid racemization in teeth. A comparison of data for aspartic acid, glutamic acid and alanine].[通过牙齿中氨基酸消旋化进行年龄估计。天冬氨酸、谷氨酸和丙氨酸数据的比较]
Kanagawa Shigaku. 1990 Dec;25(3):306-15.
4
Age estimation using the racemization of amino acid in human dentin.利用人牙本质中氨基酸的外消旋作用进行年龄估计。
J Forensic Sci. 1991 May;36(3):792-800.
5
[Estimation of age from teeth using the racemization of aspartic acid (racemization method)].[利用天冬氨酸消旋化(消旋化法)从牙齿估计年龄]
Nihon Hoigaku Zasshi. 2000 Aug;54(2):207-18.
6
[Age estimation by amino acid racemization in dentin--application of fractionation and extraction].[通过牙本质中氨基酸消旋化进行年龄估计——分级分离和提取的应用]
Kanagawa Shigaku. 1989 Sep;24(2):290-300.
7
Comparative analysis of aspartic acid racemization methods using whole-tooth and dentin samples.采用全牙和牙本质样本的天冬氨酸外消旋方法的比较分析。
Forensic Sci Int. 2012 Nov 30;223(1-3):198-201. doi: 10.1016/j.forsciint.2012.08.043. Epub 2012 Sep 16.
8
Estimation of dental age using HPLC-technique to determine the degree of aspartic acid racemization.使用高效液相色谱技术测定天冬氨酸消旋程度来估计牙龄。
J Forensic Sci. 1994 Nov;39(6):1425-31.
9
Estimation of age from teeth by amino acid racemization: influence of fixative.通过氨基酸消旋作用从牙齿估计年龄:固定剂的影响。
J Forensic Sci. 1997 Jan;42(1):137-9.
10
Degradation of biomolecules in artificially and naturally aged teeth: implications for age estimation based on aspartic acid racemization and DNA analysis.人工老化和自然老化牙齿中生物分子的降解:对基于天冬氨酸消旋化和DNA分析的年龄估计的影响。
Forensic Sci Int. 2008 Aug 6;179(2-3):181-91. doi: 10.1016/j.forsciint.2008.05.017. Epub 2008 Jul 14.

引用本文的文献

1
Aspartic acid racemization of root dentin used for dental age estimation in a Polish population sample.用于波兰人群样本牙齿年龄估计的牙根牙本质天冬氨酸消旋化
Forensic Sci Med Pathol. 2018 Sep;14(3):285-294. doi: 10.1007/s12024-018-9984-8. Epub 2018 May 2.
2
Age assessment based on third molar mineralisation : An epidemiological-radiological study on a Central-European population.基于第三磨牙矿化的年龄评估:一项针对中欧人群的流行病学-放射学研究。
J Orofac Orthop. 2017 Mar;78(2):97-111. doi: 10.1007/s00056-016-0063-z. Epub 2016 Nov 28.
3
Age estimation based on aspartic acid racemization in human sclera.
基于人巩膜中天冬氨酸消旋化的年龄估计。
Int J Legal Med. 2016 Jan;130(1):207-11. doi: 10.1007/s00414-015-1255-6. Epub 2015 Aug 25.
4
Estimation of age at death based on aspartic acid racemization in elastic cartilage of the epiglottis.基于会厌弹性软骨中天冬氨酸消旋化对死亡年龄的估计。
Int J Legal Med. 2014 Nov;128(6):995-1000. doi: 10.1007/s00414-013-0940-6. Epub 2013 Nov 12.
5
Are ancient proteins responsible for the age-related decline in health and fitness?远古蛋白质是否是导致与年龄相关的健康和体能下降的原因?
Rejuvenation Res. 2010 Feb;13(1):83-9. doi: 10.1089/rej.2009.0938.
6
Racemization in enamel among different types of teeth from the same individual.同一人不同类型牙齿牙釉质中的消旋作用。
Int J Legal Med. 2005 Mar;119(2):66-9. doi: 10.1007/s00414-004-0506-8. Epub 2005 Jan 12.
7
Predicting protein decomposition: the case of aspartic-acid racemization kinetics.预测蛋白质分解:天冬氨酸消旋动力学的案例
Philos Trans R Soc Lond B Biol Sci. 1999 Jan 29;354(1379):51-64. doi: 10.1098/rstb.1999.0359.
8
Age estimation in biopsy specimens of dentin.
Int J Legal Med. 1995;108(3):135-9. doi: 10.1007/BF01844824.
9
Postmortem estimation of age at death based on aspartic acid racemization in dentin: its applicability for root dentin.基于牙本质中天冬氨酸消旋化的死后死亡年龄估计:其在牙根牙本质中的适用性。
Int J Legal Med. 1993;105(5):289-93. doi: 10.1007/BF01370387.
10
Estimation of chronologic age using the aspartic acid racemization method. II. On human cortical bone.
Int J Legal Med. 1995;108(1):24-6. doi: 10.1007/BF01845612.