Walton Judie, Mahajan Sanjeev, Paxinos Anastasios, Marshall Jeanette, Bryant Carl, Shnier Ron, Quinn Richard, Murrell George A C
Sports Medicine and Shoulder Service, Orthopaedic Research Institute, St. George Hospital Campus, University of New South Wales, Kogarah, Sydney, New South Wales 2217, Australia.
J Bone Joint Surg Am. 2004 Apr;86(4):807-12. doi: 10.2106/00004623-200404000-00021.
This prospective study was performed to determine which clinical and imaging tests were most helpful for diagnosing acromioclavicular joint pain.
Of 1037 patients with shoulder pain, 113 who mapped pain within an area bounded by the midpart of the clavicle and the deltoid insertion were eligible for inclusion in the study. Forty-two subjects agreed to participate, and four of them were lost to follow-up. Twenty clinical tests, radiography, bone-scanning, magnetic resonance imaging, and an acromioclavicular joint injection test were performed on all patients. The patients were divided into two groups according to whether they had a > or =50% decrease in pain following the acromioclavicular joint injection. Statistical analysis, including multivariate regression analysis, was performed in order to evaluate the diagnostic effectiveness of the various tests.
Acromioclavicular joint pain was confirmed in twenty-eight of the thirty-eight patients. The most sensitive tests were examination for acromioclavicular tenderness (96% sensitivity), the Paxinos test (79%), magnetic resonance imaging (85%), and bone-scanning (82%), but these studies had low specificity. In the stepwise regression model, with the response to the injection used as the dependent variable, bone-scanning and the Paxinos test were the only independent variables retained. Patients with a positive Paxinos test as well as a positive bone scan had high post-test odds (55:1) and a 99% post-test probability of having pain due to pathological changes in the acromioclavicular joint. The likelihood ratio for patients with one negative test and one positive test was indeterminate (0.4:1). Patients with both a negative Paxinos test and a negative bone scan had a likelihood ratio of 0.03:1 for having acromioclavicular joint pain, which basically rules out the disorder.
The highly sensitive tests had low specificity, and the highly specific tests had low sensitivity. However, the combination of a positive Paxinos test and a positive bone scan predicted damage to the acromioclavicular joint as the cause of shoulder pain with a high degree of confidence.
本前瞻性研究旨在确定哪些临床和影像学检查对诊断肩锁关节疼痛最有帮助。
在1037例肩部疼痛患者中,113例疼痛部位位于锁骨中部和三角肌止点所界定区域内的患者符合纳入本研究的条件。42名受试者同意参与,其中4人失访。对所有患者进行了20项临床检查、X线摄影、骨扫描、磁共振成像以及肩锁关节注射试验。根据肩锁关节注射后疼痛是否减轻≥50%,将患者分为两组。进行了包括多因素回归分析在内的统计学分析,以评估各项检查的诊断效能。
38例患者中28例确诊为肩锁关节疼痛。最敏感的检查是肩锁关节压痛检查(敏感性96%)、帕西诺斯试验(79%)、磁共振成像(85%)和骨扫描(82%),但这些检查的特异性较低。在逐步回归模型中,以注射反应作为因变量,骨扫描和帕西诺斯试验是仅保留的自变量。帕西诺斯试验阳性且骨扫描阳性的患者试验后概率较高(55:1),因肩锁关节病理改变导致疼痛的试验后概率为99%。一项检查阴性而另一项检查阳性的患者似然比不确定(0.4:1)。帕西诺斯试验和骨扫描均为阴性的患者发生肩锁关节疼痛的似然比为0.03:1,基本可排除该疾病。
高敏感性检查特异性低,高特异性检查敏感性低。然而,帕西诺斯试验阳性和骨扫描阳性相结合,高度提示肩锁关节损伤是肩部疼痛的原因。