通过叠氮化物捕获终止基于锰（III）的氧化环化反应。
Termination of Mn(III)-based oxidative cyclizations by trapping with azide.
作者信息
Snider Barry B, Duvall Jeremy R
机构信息
Department of Chemistry, MS 015, Brandeis University, Waltham, MA 02454-9110, USA.
出版信息
Org Lett. 2004 Apr 15;6(8):1265-8. doi: 10.1021/ol049805s.
PMID:15070313
Abstract
The radicals formed in Mn(III)-based oxidative free-radical cyclizations of beta-keto esters and malonate esters can be trapped with sodium azide and Mn(III) to give cyclic and bicyclic azides in 30-80% yield. Reduction of the azide gives bi- and tricyclic lactams. [reaction: see text]
摘要
在β-酮酯和丙二酸酯基于锰（III）的氧化自由基环化反应中形成的自由基，可以用叠氮化钠和锰（III）捕获，以30 - 80%的产率得到环状和双环叠氮化物。叠氮化物的还原得到双环和三环内酰胺。[反应：见原文]
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