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[多发性硬化症和急性脱髓鞘性多发性神经病患者的临床和神经生理指标比较分析]

[Comparative analysis of clinical and neurophysiological indices in patients with multiple sclerosis and acute demyelinating polyneuropathy].

作者信息

Nikitina V V, Skoromets A A, Barbas I M, Iantareva L I, Pospelova M L

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 2004;104(3):52-4.

Abstract

A comparison study of some clinical and neuropsychological indices in two demyelinating disorders--multiple sclerosis (17 patients, mean age 31.6 years) and inflammatory demyelinating polyneuropathy (7 patients, mean age 49.5 years) was conducted, using electromyography with registration of impulse velocity conduction along the nerve and M-responses as well as of the parameters of movement units potentials. The data obtained suggest the presence of demyelinating lesions of central and peripheral nervous systems, namely, symptoms of axonal demyelinating polyneuropathy with the prevalence of demyelinating process, its dissemination and generalization, in both disorders.

摘要

对两种脱髓鞘疾病——多发性硬化症(17例患者,平均年龄31.6岁)和炎性脱髓鞘性多发性神经病(7例患者,平均年龄49.5岁)的一些临床和神经心理学指标进行了比较研究,采用肌电图记录沿神经的冲动速度传导、M反应以及运动单位电位参数。所获得的数据表明,在这两种疾病中均存在中枢和周围神经系统的脱髓鞘病变,即轴索性脱髓鞘性多发性神经病的症状,脱髓鞘过程占优势,且有其播散和泛化。

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