Terada H, Kazui T, Yamashita K, Washiyama N, Suzuki K, Suzuki T, Okura K, Suzuki M
First Department of Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Kyobu Geka. 2004 Apr;57(4):307-12.
The purpose of this study was to review retrospectively recent results in 75 patients undergoing thoracoabdominal aortic operations using the technique of distal aortic perfusion with segmental aortic clamping. Between July 1997 and November 2003, 46 males (61%) and 29 females (39%) were treated. The patients ranged in age from 26 to 82 (mean 63 +/- 13) years. Indications for surgery included dissecting thoracoabdominal aortic aneurysm (n = 28), atherosclerotic thoracoabdominal aortic aneurysm (n = 46), and traumatic aneurysm (n = 1). Emergency operation was performed in 8 (11%). The extent of aneurysm was Crawford type I in 12 patients, type II in 19, type III in 34, and type IV in 10. Profound hypothermic circulatory arrest was used in 3 patients and retrograde segmental clamping technique in 5. Cerebrospinal fluid drainage and naloxone hydrochloride administration were performed as adjunctive methods since February 2000. There were 6 (8%) in-hospital deaths. The overall incidence of postoperative paraplegia or paraparesis was 8% (6/75). Although the survival rate has improved, the problem of a complete prevention of ischemic spinal cord injury on the thoracoabdominal aortic operations remains unsolved. The multimodality approach is needed to reduce the risk of this devastating complication.
本研究的目的是回顾性分析75例采用主动脉远端灌注联合节段性主动脉钳夹技术进行胸腹主动脉手术的近期结果。1997年7月至2003年11月期间,共治疗46例男性(61%)和29例女性(39%)。患者年龄在26至82岁之间(平均63±13岁)。手术指征包括胸主动脉夹层动脉瘤(n = 28)、动脉粥样硬化性胸主动脉瘤(n = 46)和创伤性动脉瘤(n = 1)。8例(11%)患者进行了急诊手术。动脉瘤范围为Crawford I型12例,II型19例,III型34例,IV型10例。3例患者采用了深低温停循环,5例采用了逆行节段性钳夹技术。自2000年2月起,采用脑脊液引流和盐酸纳洛酮作为辅助方法。住院死亡6例(8%)。术后截瘫或轻瘫的总发生率为8%(6/75)。尽管生存率有所提高,但胸腹主动脉手术中完全预防缺血性脊髓损伤的问题仍未解决。需要采用多模式方法来降低这种毁灭性并发症的风险。